1505 #4 - Chpt 6: Genetics (Book Questions)

Patients with an X-linked hereditary condition: a. are generally affected more severely if they are men b. are always XYY c. have cells with an extra Barr body d. are always women

a. are generally affected more severely if they are men

The cause of all forms of labial and palatal clefting is considered to be: a. multifactorial b. environmental c. autosomal recessive d. autosomal dominant

a. multifactorial

Which of the following is true for von Recklinghausen disease? a. patients may have gingival neurofibromas b. it is inherited as an autosomal recessive trait c. patients experience a generalized whitening of the oral mucosa d. patients have multiple fibromatoses

a. patients may have gingival neurofibromas

In dentinogenesis imperfecta type II, teeth have: a. roots that are short and thin b. dilacerated roots c. hard, dense dentin d. markedly brittle enamel

a. roots that are short and thin

Cannon disease is also known as: a. white sponge nevus b. gingival fibromatosis c. chronic neutropenia d. cherubism

a. white sponge nevus

The karyotype of a patient with Turner syndrome shows: a. 43 autosomes and XYY b. 44 autosomes and XO c. 44 autosomes and XYY d. 44 autosomes and XXY

b. 44 autosomes and XO

Hypothetically, an autosomal dominant trait would be clinically present in: a. 25% of the offspring of an affected parent b. 50% of the offspring of an affected parent c. 75% of the offspring of an affected parent d. only in males, never in female offspring

b. 50% of the offspring of an affected parent

In all inherited varieties of gingival fibromatosis, the gingival enlargement is characterized by a marked: a. alveolar bone hypertrophy b. collagenization of the connective tissue c. hyperplasia of the covering epithelium d. chronic inflammatory cellular infiltrate

b. collagenization of the connective tissue

All of the following are involved in cherubism except one. Which one is the exception? a. coronoid process b. condyle c. posterior mandible d. ascending ramus

b. condyle

The most frequent site of hemorrhage in patients with with hereditary hemorrhagic telangiectasia is the: a. lip mucosa b. gingiva c. nasal mucosa d. eyelids

b. gingiva

Torus mandibularis and torus palatinus are: a. sporadic traits b. inherited as an autosomal dominant trait c. inherited as an autosomal recessive trait d. more prevalent in males

b. inherited as an autosomal dominant trait

Which of the following is a component of the Peutz-Jeghers syndrome? a. multiple jaw cysts b. multiple pigmented macules on the lower lip and mucosa c. multiple nodules on the tip of the tongue d. multiple supernumerary teeth

b. multiple pigmented macules on the lower lip and mucosa

The characteristic finding in permanent teeth affected with coronal dentin dysplasia is: a. large, square pulp chambers in molars b. thistle shaped pulp chambers in incisors c. crowns with amber color d. markedly short roots

b. thistle shaped pulp chambers in incisors

Snow capped amelogenesis imperfecta have teeth with: a. short, blunted roots b. white, hypocalcified enamel at the incisal and occlusal thirds c. thin, brown enamel d. obliterated pulp chambers

b. white, hypocalcified enamel at the incisal and occlusal thirds

Taurodontic teeth: a. have long roots b. have thistle shaped pulp chambers c. are pyramidal in shape d. are supernumerary

c. are pyramidal in shape

The Papillon-Lefevre syndrome is inherited according to a (an): a. X-linked recessive pattern b. autosomal dominant pattern c. autosomal recessive pattern d. X-linked dominant pattern

c. autosomal recessive pattern

Which of the following is the most serious component of Gardner syndrome: a. teeth hypercementosis b. mandibular odontomas c. colorectal polyposis d. multiple osteomas

c. colorectal polyposis

Which one of the following is associated with cyclic neutropenia? a. exfoliating teeth b/c of short roots b. chipping away of enamel c. diminished number of circulating neutrophils d. premature loss of primary teeth

c. diminished number of circulating neutrophils

Patients with hypohidrotic ectodermal dysplasia characteristically have: a. blue sclera b. excessive amounts of hair c. hypodontia d. multiple tongue nodules

c. hypodontia

Which of the following is characteristically assoc. with teeth with large pulp chambers? a. coronal dentin dysplasia b. dentinogenesis imperfecta c. hypophophatasia d. pittef autosomal dominant amelogenesis imperfecta

c. hypophophatasia

Two characteristic clinical components of mandibulofacial dysostosis are: a. lack of clavicles and delayed teeth eruptions b. hypodontia and dysplastic nails c. hypoplastic mandible and deafness d. cleft lip and fistulas of lower lip

c. hypoplastic mandible and deafness

Odontogenic keratocysts are a clinical component of: a. cherubism b. pegged lateral incisors c. nevoid basal cell carcinoma syndrome d. neurofibromatosis of von Recklinghausen

c. nevoid basal cell carcinoma syndrome

A 9 yr. old boy exhibits markedly swollen red and bleeding gingiva. In addition, he has tooth mobility, and the intraoral radiographs show marked alveolar bone atrophy with vertical periodontal pockets. Which of the following will be found in this child if he were to have Papillon-Lefevre syndrome? a. lack of anterior vestibular sulcus b. diminished sweating c. palmar and plantar hyperkeratosis d. blue sclerae

c. palmar and plantar hyperkeratosis

Radiographs of a patient with radicular dentin dysplasia show: a. taurondontic teeth b. large pulp chambers with long pulp horns c. pulp chambers with a half moon appearance d. internal resorption of teeth

c. pulp chambers with a half moon appearance

A 19 yr. old woman is diagnose with cleidocranial dysplasia. She has absent clavicles and a mushroom shaped skull. Which of the following conditions is she also most likely to have? a. large pulp chambers b. taurontodism c. supernumerary teeth d. pegged lateral incisors

c. supernumerary teeth

Patients with hypophosphatasia characteristically have: a. increase in serum alkaline phosphatase levels b. obliterated pulp chambers c. marked gingival keratinization d. absence of root cementum

d. absence of root cementum

All of the following are characteristics of cherubism except one. Which is the exception? a. pseudoanodontia b. autosomal dominant c. ocular hypertelorism d. autosomal recessive

d. autosomal recessive

A 14 yr. old boy is seen in consultation because of bilateral mandibular swelling. Radiographs show a bilateral multilocular lesion in the ascending mandibular rami. The mother of this patient has similar findings. The most likely diagnosis is: a. cleidocranial dysplasia b. nevoid basal cell carcinoma syndrome c. Ellis-Van Creveld syndrome d. cherubism

d. cherubism

In which one of the following conditions can the shoulders be brought forward to the midline due to hypoplastic clavicles? a. cherubism b. Ellis-von Creveld syndrome c. Turner syndrome d. cleidocranial dysplasia

d. cleidocranial dysplasia

Hypotrichosis means: a. increased number of sweat glands b. diminished number of sweat glands c. increased amount of hair d. decreased amount of hair

d. decreased amount of hair

The major concern for a dental hygienist when treating a patient with Osler-Rendu-Parkes Weber syndrome should be: a. severe infection b. epithelial desquamation c. spontaneous ulceration d. gingival hemorrhage

d. gingival hemorrhage

The so-called "enamel agenesis" is one of which type of amelogenesis imperfecta? a. hypocalcified b. hypomaturation c. hypoplastic-hypomaturation d. hypoplastic

d. hypoplastic

The most frequently exfoliated teeth in patients with hypophosphatasia are the: a. mandibular permanent incisors b. mandibular primary incisors c. maxillary primary molars d. maxillary primary incisors

d. maxillary primary incisors

Which one of the following statements is true when comparing cyclic neutropenia and Kostmann syndrome? a. oral lesions in cyclic neutropenia are more severe b. both conditions are inherited as autosomal dominant c. both conditions are assoc. with capillary fragility d. oral lesions in Kostmann syndrome are always present unless systemic treatment is instituted.

d. oral lesions in Kostmann syndrome are always present unless systemic treatment is instituted.

Trisomy refers to: a. one extra chromosome in each pair b. three extra chromosomes c. the presence of two extra X chromosomes in a male d. pair of chromosomes with an identical extra chromosome

d. pair of chromosomes with an identical extra chromosome