3-7
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TLR-4
- LPS (Gram-negative bacteria) - dendritic cells - macrophages
TLR-3
- dsRNA (viruses) - macrophages - cDCs - intestinal epithelial cells
TLRs are expressed on...
- macrophages - dendritic cells - B cells - stromal cells - certain epithelial cells
TLR-7
- ssRNA (viruses) - only on pDCs and B cells
TLR-1:TLR-2
1. mycobacteria 2. gram-positive bacteria 3. fungi 4. diacyl and triacyl lipopeptides
TLR-9
DNA with unmethylated CpG 1. bacteria 2. DNA viruses