AP BIO sem1 ss6
Which of the following statements accurately uses the information presented to support the hypothesis that interruption of M function in a single body cell can result in cancer?
Growth-factor signaling can trigger mitosis in cells that are in direct contact with other cells.
The model shown in the figure represents the role of two hormones, calcitonin and parathyroid hormone (PTH), in maintaining normal blood calcium levels in humans. If a dietary change results in an increase in blood calcium concentration above normal levels, which of the following is the most likely effect on calcium homeostasis?
Calcitonin levels will rise, thus promoting the deposit of calcium into bones.
The brain coordinates the circulatory and respiratory systems of the human body. The control of breathing, for example, involves neural pathways among the structures represented in the figure above. One important stimulus in the control of breathing is an increase in blood CO2 concentration, which is detected as a decrease in blood pH. Which of the following best describes the physiological response to an overall increase in cellular respiration in the body?
In response to low blood pH, the pH sensors send a signal to the brain, which then sends a signal to the diaphragm, resulting in an increased rate of breathing to help eliminate excess blood CO2 .
Cortisol is a hormone produced in response to stress, including starvation, in humans. Which of the following is most likely an immediate effect of a starvation-induced increase in cortisol secretion?
Increased mobilization of fatty acids from fat cells
Which of the following is true of mitosis?
It maintains the same chromosome number in the daughter cells as in the parent cell.
Based on the model of eukaryotic cell cycle regulation shown in the figure, which of the following best describes the effect of a drug that blocks the production of the mitotic cyclin?
The cell would be prevented from entering mitosis, and the cell would stop dividing.
Thyroxin is a hormone that increases metabolic activities within various tissue targets. Low levels of circulating thyroxin trigger the secretion of thyroid-stimulating hormone (TSH) from the anterior pituitary. TSH secretion then stimulates thyroxin production and release by the thyroid gland. The increased level of circulating thyroxin inhibits further secretion of TSH from the anterior pituitary.Based on the information provided, which of the following can most likely be concluded about the TSH-thyroxin loop?
The feedback mechanism would maintain relatively constant levels of thyroxin throughout tissue targets.
Which of the following statements best describes how a growth factor stimulates cell division from outside a cell?
The growth factor binds to receptors on the cell surface, initiating a signal transduction pathway that activates specific target genes.
Based on the data in Figure 2, which of the following best justifies the researchers' claim that hESC-β implants can functionally replace the mouse's naturally occurring β-cells?
The mouse with an hESC-β implant successfully regulated blood glucose levels after STZ treatment but not after the implant was removed.
In contrast to type 1 diabetes, where there is no insulin production, type 2 diabetes is characterized by a failure of body cells to respond normally to insulin. Based on the results of the experiment, which of the following best predicts the effectiveness of using hESC-β implantation to treat type 2 diabetes?
The treatment would fail because insulin produced by implanted hESC-β cells will not stimulate glucose uptake by body cells.
One approach to treating patients with pancreatic cancer and other cancers in which the Hedgehog protein is detected is to modify the Hedgehog signaling pathway. Which of the following is the most useful approach?
Treating patients with a membrane-soluble compound that can bind to Smo and block its activity
Cancer can result from a variety of different mutational events. Which of the following is LEAST likely to result in the initiation of a cancerous tumor?
A defect in a cell-cycle checkpoint prevents a cell from entering the S phase.
The diagram above represents a model of signal transduction pathways (I and II) in a cell that is targeted by two different hormones (H1 and H2). The components of the signal transduction pathways are identified in the figure legend. Each cellular molecule in both pathways can exist in an inactive or active form. When the components in pathway I are sequentially activated, the TAP molecules promote cell division. When the components in pathway II are sequentially activated, downstream signaling by the G protein is inhibited. Based on the model, which of the following mutations is most likely to result in a cell that will generate a cancerous tumor?
A mutation in the gene encoding G-PIP that results in a nonfunctional protein
The figure above shows a model of a ligand precursor being cleaved to produce an active ligand that binds to a specific receptor. Which of the following is most likely to reduce the binding of the active ligand to its receptor?
A mutation in the receptor gene that causes a substitution of a charged amino acid for a nonpolar amino acid in the ligand binding site of the receptor
Cell communication is critical for the function of both unicellular and multicellular eukaryotes. Which of the following is likely true of cell signaling?
Similar cell signaling pathways in diverse eukaryotes are evidence of conserved evolutionary processes.
