A/P Lab 29

A normal red blood cell count is __

4- 6 million/mm3 of blood

The total white blood cell count ranges from ________ to ________ /mm3 of blood.

4800, 10,800

You performed a blood typing activity as described in the lab manual. You observed agglutination (clumping) with anti-B and anti-Rh serum. Based on the test results you can conclude that the blood type you tested was ___

B+

__________ are the leukocytes responsible for releasing histamine and other mediators of inflammation

Basophils

What is a hematocrit?

Hematocrit is the percentage of erythrocytes in a whole blood sample

A person with type AB blood receives a transfusion of type O blood. Will there be a transfusion reaction? Why or why not?

No: the recipient has no antibodies to antigens A and B, and therefore can receive blood from a type O donor

A person with type B- blood receives a transfusion of type O+ blood. It is his very first blood transfusion. Will there be a transfusion reaction? Why or why not?

No: the recipient has no antibodies to the Rh factor because this is his first transfusion

Which of these makes up the greatest portion of whole blood by volume?

Plasma typically constitutes 55% of whole blood, although this value can vary somewhat

Plasmapheresis is a procedure in which blood is removed, its plasma is separated from the formed elements, and the formed elements are returned to the patient or donor. Kidney transplants usually require that the donor and recipient have the same blood type. If plasmapheresis is administered to the patient before and after the transplant surgery, rejection of the kidney is less likely to occur. Explain why.

Plasmapheresis removes the soluble components in the blood that can trigger a rejection reaction, such as antibodies (globulins)

Which of these is true of the materials making up the buffy coat in centrifuged blood?

They are intermediate in density between erythrocytes and plasma

What is true about blood typing?

Type AB blood contains antigens A and B.

Bleeding disorders may result from thrombocytopenia, a deficiency of platelets. Which part of hemostasis does not require platelets?

Vascular spasm-This is the first event to occur in response to a tear in the blood vessel wall. Although two platelet factors (serotonin and thromboxane A2) enhance vascular spasms, these spasms are not dependent on platelets

Blood typing is based on the presence of proteins known as __________ on the outer surface of the red blood cell plasma membrane

antigens

Which of the following white blood cells are granulocytes?

basophils and neutrophils

A patient reports to the doctor that she bruises very easily, and when she cuts herself, she has a hard time stopping the bleeding. What test might a health care provider order to help diagnose this problem?

coagulation time

You can recognize these white blood cells because they have a bilobed nucleus and red granules in the cytoplasm.

eosiniphil

These white blood cells kill parasitic worms and play a complex role in allergic responses and asthma.

eosinophils

Mature __________ are the most numerous blood cells and do not have a nucleus.

erythrocytes

The final step in coagulation is the formation of _

fibrin

Normally, the amount of plasma in whole blood is ________ than the amount of formed elements; plasma makes up approximately ________ percent of whole blood

greater; 55

A person who has symptoms of paleness and chronic fatigue is suspected of having anemia. To investigate this suspicion further, it would be most helpful to measure _

hematocrit

When determining the __________, you will centrifuge whole blood in order to allow the formed elements to sink to the bottom of the sample

hematocrit

From the choices listed here, the most accurate way to assess the oxygen-carrying capacity of the blood is probably to measure the _

hemoglobin content

The normal hematocrit value for __________ is generally higher than that of the opposite sex

males

Leukopenia ___

may indicate a disease such as cirrhosis of the liver or tuberculosis

Platelets are cell fragments of large multinucleate cells called __

megakaryocytes

The least numerous but largest of all agranulocytes is the ____

monocyte

This cell is the largest white blood cell. It lacks cytoplasmic granules and has a kidney-shaped nucleus

monocyte

These are the most abundant leukocytes, constituting 40-70% of all white blood cells.

neutrophils

Granulocytes include ____

neutrophils, eosinophils, basophils

This component of blood plasma includes molecules that are important for body defense, osmotic balance, and lipid transport.

plasma proteins

This formed element is essential for blood clotting.

platelets

Three types of formed elements found in blood include erythrocytes, leukocytes, and __

platelets

_________ are essential for blood clotting.

platelets

A blood test reveals a large increase in the number of RBCs. One possible explanation for this may be __

polycythemia

The most numerous blood cells are __

red blood cells

The hematocrit measures __

the volume of RBC in a blood sample

If an individual is transfused with the wrong blood type, the recipient's antibodies react with the donor's antigens, eventually clumping and hemolyzing the donated RBCs.

true