ATI Dosage Calculation and Safe Medication Administration 3.0 - Powdered Medications

A nurse is preparing to administer ampicillin 1.5 g IV bolus. The nurse reconstitutes a vial of ampicillin to yield a final concentration of 30 mg/mL. How many mL should the nurse administer?

50 mL Rationale: 1. 1.5 g = 1,500 mg 2. 30 mg/1 mL = 1,500 mg/x mL 3. 30x = 1,500 4. x = 50 mL

A nurse is preparing to administer ziprasidone 12.5 mg IM to an adolescent. The nurse reconstitutes a vial of ziprasidone to yield a final concentration of 20 mg/mL. How many mL should the nurse administer? (Round to the nearest tenth.)

0.6 mL Rationale: 1. 20 mg/1 mL = 12.5 mg/x mL 2. 20x = 12.5 3. x = 0.625 mL 4. x = 0.6 mL (rounded)

A nurse is preparing to administer ceftriaxone 250 mg IM. The nurse reconstitutes a vial of ceftriaxone to yield a final concentration of 350 mg/mL. How many mL should the nurse administer? (Round to the nearest tenth.)

0.7 mL Rationale: 1. 350 mg/1 mL = 250 mg/x mL 2. 350x = 250 3. x = 0.7142857 mL 4. x = 0.7 mL (rounded)

A nurse is preparing to administer ceftriaxone 0.5 g IM. The nurse reconstitutes a vial of ceftriaxone to yield a final concentration of 350 mg/mL. How many mL should the nurse administer? (Round to the nearest tenth.)

1.4 mL Rationale: 1. 0.5 g = 500 mg 2. 350 mg/1 mL = 500 mg/x mL 3. 350x = 500 4. x = 1.42857 mL 5. x = 1.4 mL (rounded)

A nurse is preparing to administer nafcillin 375 mg IM to a school-age child. Available is nafcillin powder for injection 2 g vial. The nurse reconstitutes the vial to yield a final concentration of 250 mg/mL. How many mL should the nurse administer?

1.5 mL Rationale: 1. 250 mg/1 mL = 375 mg/x mL 2. 250x = 375 3. x = 1.5 mL

A nurse is preparing to administer pentamidine 1.75 mg IM. The nurse reconstitutes a vial of pentamidine to yield a final concentration of 100 mg/mL. How many mL should the nurse administer? (Round to the nearest tenth.)

1.8 mL Rationale: 1. 100 mg/1 mL = 175 mg/x mL 2. 100x = 175 3. x = 1.75 mL 4. x = 1.8 mL (rounded)

A nurse is preparing to administer cefaclor 400 mg PO. The nurse reconstitutes a container of cefaclor to yield a final concentration of 187 mg/5 mL. How many mL should the nurse administer? (Round to the nearest tenth.)

10.7 mL Rationale: 1. 187 mg/5 mL = 400 mg/x mL 2. 187x = 2,000 3. x = 10.695187 mL 4. x = 10.7 mL (rounded)

A nurse is preparing to administer cefazolin 1.5 g IV bolus to a client who has fluid restrictions. The nurse reconstitutes a vial of cefazolin to yield a final concentration of 138 mg/mL. How many mL should the nurse administer? (Round to the nearest tenth.)

10.9 mL Rationale: 1. 1.5 g = 1,500 mg 2. 138 mg/1 mL = 1,500 mg/x mL 3. 138x = 1,500 4. x = 10.869565 mL 5. x = 10.9 mL (rounded)

A nurse is preparing to administer clindamycin 0.2 g PO. The nurse reconstitutes a vial of clindamycin powder to yield a final concentration of 75 mg/5 mL. How many mL should the nurse administer? (Round to the nearest tenth.)

13.3 mL Rationale: 1. 0.2 g = 200 mg 2. 75 mg/5 mL = 200 mg/x mL 3. 75x = 1,000 4. x = 13.33333 mL 5. x = 13.3 mL (rounded)

A nurse is preparing to administer nafcillin 0.5 g IM. The nurse reconstitutes a vial of nafcillin to yield a final concentration of 250 mg/mL. How many mL should the nurse administer?

2 mL Rationale: 1. 0.5 g = 500 mg 2. 250 mg/1 mL = 500 mg/x mL 3. 250x = 500 4. x = 2 mL

A nurse is preparing to administer levothyroxine 200 mcg IV bolus. The nurse reconstitutes a vial of levothyroxine to yield a final concentration of 100 mcg/mL. How many mL should the nurse administer?

2 mL Rationale: 1. 100 mcg/1 mL = 200 mcg/x mL 2. 100x = 200 3. x = 2 mL

A nurse is preparing to administer oxacillin 375 mg IM. The nurse reconstitutes a vial of oxacillin to yield a final concentration of 250 mg/1.5 mL. How many mL should the nurse administer? (Round to the nearest tenth.)

2.3 mL Rationale: 1. 250 mg/1.5 mL = 375 mg/x mL 2. 250x = 562.5 3. x = 2.25 mL 4. x = 2.3 mL

A nurse is preparing to administer levothyroxine 0.3 mg IV bolus. The nurse reconstitutes a vial of levothyroxine to yield a final concentration of 100 mcg/mL. How many mL should the nurse administer?

3 mL Rationale: 1. 0.3 mg = 300 mcg 2. 100 mcg/1 mL = 300 mcg/x mL 3. 100x = 300 4. x = 3 mL

A nurse is preparing to administer ampicillin 0.75 g IM every 6 hours to a client. The nurse reconstitutes a vial of ampicillin to yield a final concentration of 250 mg/mL. How many mL should the nurse administer?

3 mL Rationale: 1. 0.75 g = 750 mg 2. 250 mg/1 mL = 750 mg/x mL 3. 250x = 750 4. x = 3 mL

A nurse is preparing to administer clindamycin 450 mg PO. The nurse reconstitutes a vial of clindamycin powder to yield a final concentration of 75 mg/5 mL. How many mL should the nurse administer?

30 mL Rationale: 1. 75 mg/5 mL = 450 mg/x mL 2. 75 x = 2,250 3. x = 30 mL

A nurse is preparing to administer hydrocortisone 200 mg intermittent IV bolus. Available is hydrocortisone powder for injection 1 g vial. The nurse reconstitutes a vial of hydrocortisone to yield a final concentration of 50 mg/mL. How many mL should the nurse administer?

4 mL Rationale: 1. 50 mg/1 mL = 200 mg/x mL 2. 50x = 200 3. x = 4 mL

A nurse is preparing to administer amoxicillin 325 mg PO. The nurse reconstitutes a vial of amoxicillin to yield a final concentration of 400 mg/5 mL. How many mL should the nurse administer? (Round to the nearest tenth.)

4.1 mL Rationale: 1. 400 mg/5 mL = 325/x mL 2. 400x = 1,625 3. x = 4.0625 mL 4. x = 4.1 mL (rounded)

A nurse is preparing to administer cefazolin 500 mg IV bolus. The nurse reconstitutes a vial of cefazolin to yield a final concentration of 100 mg/mL. How many mL should the nurse administer?

5 mL Rationale: 1. 100 mg/1 mL = 500 mg/x mL 2. 100x = 500 3. x = 5 mL

A nurse is preparing to administer oxacillin 500 mg IV bolus. The nurse reconstitutes a vial of oxacillin to yield a final concentration of 100 mg/mL. How many mL should the nurse administer?

5 mL Rationale: 1. 100 mg/1 mL = 500 mg/x mL 2. 100x = 500 3. x = 5 mL

A nurse is preparing to administer fluconazole 200 mg PO. The nurse reconstitutes a container of fluconazole powder for oral suspension to yield a final concentration of 40 mg/mL. How many mL should the nurse administer?

5 mL Rationale: 1. 40 mg/1 mL = 200 mg/x mL 2. 40x = 200 3. x = 5 mL

A nurse is preparing to administer daptomycin 360 mg IV bolus. The nurse reconstitutes a vial of daptomycin to yield a final concentration of 0.5 g/10 mL. How many mL should the nurse administer?

7.2 mL Rationale: 1. 0.5 g = 500 mg 2. 500 mg/10 mL = 360 mg/x mL 3. 500x = 3,600 4. x = 7.2 mL

A nurse is preparing to administer 375 mg of cephalexin PO. The nurse reconstitutes a vial of cephalexin powder to yield a final concentration of 0.25 g/5 mL. How many mL should the nurse administer? (Round to the nearest tenth.)

7.5 mL Rationale: 1. 0.25 g = 250 mg 2. 250 mg/5 mL = 375 mg/x mL 3. 250x = 1,875 4. x = 7.5 mL

A nurse is preparing to administer amoxicillin 775 mg PO. The nurse reconstitutes a container of amoxicillin to yield a final concentration of 400 mg/5 mL. How many mL should the nurse administer? (Round to the nearest tenth.)

9.7 mL Rationale: 1. 400 mg/5 mL = 775 mg/x mL 2. 400x = 3,875 3. x = 9.6875 mL 4. x = 9.7 mL (rounded)

A nurse is preparing to administer nystatin 400,000 units PO. Available is nystatin powder 500,000 units/0.125 teaspoon. The nurse reconstitutes a vial of nystatin to yield a final concentration of 500,000 units/120 mL. How many mL should the nurse administer?

96 mL Rationale: 1. 500,000 units/120 mL = 400,000 units/x mL 2. 500,000x = 48,000,000 3. x = 96 mL

A nurse is preparing to reconstitute and administer a powdered medication in a multidose vial. Which of the following actions should the nurse plan to take? A. Use a filtered needle to administer the medication. B. Briskly shake the medication vial after adding the diluent. C. Label the vial with the date and time before administering the medication. D. Swab the rubber seal on the vial with triclosan prior to adding the diluent.

C. Label the vial with the date and time before administering the medication. Rationale: A. The nurse should use a filtered needle to withdraw mixed liquid medications from a vial to filter out particles that could harm the client. The nurse should use a new, non-filtered needle to administer the medication to the client. B. The nurse should gently roll the medication to mix it. Shaking the medication can cause bubbles to form that could harm the client. C. The nurse should label the vial with the date, time, the nurse's initials, and the concentration of the medication to ensure safe medication administration. D. The nurse should swab the rubber seal on the medication vial with an alcohol swab to disinfect the vial before adding the diluent.