Bio test 2

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A particular triplet of bases in the template strand of DNA is 5' AGT 3'. the corresponding codon for the mRNA transcribed is

3' UCA 5'

If the sequence in the non-template strand of DNA for a particular amino acid is 5'AGT3' then the anti-codon on the corresponding tRNA would be

5'ACU3'

Which of the following DNA mutations is most likely to damage the protein it specifies

A base pair deletion

Which of the following nucleotide triplets best represents a codon

A triplet in the same reading frame as an upstream AUG

__ Of histone proteins are associated with transcription of genes and ___ of cytosine bases in DNA is associated with suppression of transcription

Acetylation and methylation

When gene regulation is controlled by positive control of transcription, binding of the regulatory proteins to DNA ___ transcription

Activates or triggers

Accuracy in the translation of mRNA into the primary structure of a polypeptide depends on specificity in the

Binding of the anti-codon to the codon and the attachment of amino acids to tRNAs

The statement "DNA is transcribed RNA, DNA is translated to proteins" is known as

Central dogma

Enhancers and silencers are __ sequences that bind to _ to control the level of transcription from specific genes

DNA and RNA poly

A mutant bacterial cell has a defective aminoacyl tRNA synthetase that attaches to a lysine to tRNAs with the anti-codon AAA instead of the normal phenylalanine. the consequence of this for the cell will be that

Proteins in the cell will include lysine instead of phenylalanine at amino acid position specified by the codon UUU

In the process of transcription...

RNA is synthesized

In eukaryotic cells transcription cannot begin until

Several transcription factors have bound to the promoter

In E. coli if RNA polymerase is missing ___ then transcription initiation would not occur at the appropriate initiation sites

Sigma

Mutation of the operator region of the lac operon such that it can't bind to lac one protein in the absence of lactose would have which of the following effects

The enzymes of the lac operon would be expressed in the presence of lactose

Once a peptide bond has formed between the amino acid attached to the tRNA in the P site and the amino acid associated with the tRNA in the A site, what occurs next?

Translocation

Which of the following is the first event to take place in translation and eukaryotes

the small subunit of the ribosome recognizes and attaches to the 5' cap of mRNA


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