BIO.151: DNA replication Quiz

If a DNA sample contains 20% adenine, the proportion of guanine is:

30%

Which enzyme catalyzes the elongation of a DNA strand in the 5' → 3' direction?

DNA polymerase III

If telomerase were not present in eukaryotic cells:

Every time a chromosome was replicated, the ends of the telomeres would get shorter

Who used X-ray crystallography of purified DNA fibers to show that DNA has helical structure, and provided the dimensions of that structure?

Franklin

DNA replication in prokaryotes differs from replication in eukaryotes for which of these reasons?

Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many

Until the mid-1940s, most scientists believed that genetic information was encoded by:

Proteins

In E. coli, there is a mutation in a gene called dnaB that alters the helicase that normally acts at the origin of replication. Which of the following would you expect as a result of this mutation?

The strands will be unable to separate, so no replication fork will be formed

Which of the following synthesizes short segments of RNA?

primase

The leading and the lagging strands differ in that:

the leading strand is synthesized continuously, whereas the lagging strand is synthesized in short fragments that are ultimately stitched together

The two strands of DNA are antiparallel; this means that:

the strands run in opposite directions