BME 3 Final

The HbA1c test measures how much of this molecule is attached to hemoglobin.

glucose

Beta carotene is a precursor to vitamin a. The caret trial showed that heavy smokers who took a daily 30mg beta carotene supplememt had:

higher rates of lung cancer than the control group

The Ames Reflective Meter was on of the first:

home based blood glucose meters

James Collip discovered that if he injected too much insulin into a rabbit it developed convulsion. This effect is known as:

hypoglycemia

The fragment of preproinsulin called c-peptide:

is not essential, people live decades without it

A black box on a prescription drug label

is used to highlight saffety concerns

Engineered e. Coli bacteria containing recombinant dna is not dangerous to humans because

it is incapable of surving outside well controlled labooratory environments

In 1969, Oregon applied fro a patent on a pregnancy test that could be performed at home. The inventors on the patent were:

just margaret crane

Congress passed the animal welfare act of 1966 after an uproar causes by the publication of an article about dog dealers in which magazine?

life magazine

James Collip needed an assay for the activity of insulin in order to develop a purification method. His assay for inuslin was based upon:

measuring the change in blood sugar levels in rabbits

NPH insulin is a modified form of insulin. The modification results in a longer acting aactivity. The modification is done by:

miixing insulin with a protein called protamine

One conclusion from the diabetes control and complications trial was that tight control:

minimized long term complications

A continous glucose monitor measures blood glucose approximately once every:

minute

Immediately after is one year surgical residency at Torontos Hospital for sick children, Fred Banting.....

opened his own practice to see patients

Arnold Beckman invented and sold one of the first integrated:

ph meters

From the 1920s through the 1960s, insulin used by patients with diabetes came from which sources:

pigs and cows

The first home pregnancy test was called:

predictor

Fred banting developed his idea on how to treat diabetes while he was:

preparing a lecture for medical students

In the 1960's Margaret Crane was working as a:

product packaging designer

A child who develops diabetes typically loses weight. In 1920 the best treatment for children would be to:

restrict diet, causing more weight loss

One of the inventors of the HbA1c test developed the test after a clinical trial involving this disease has suddenly stopped:

sickle cell

The label of a prescription drug:

summarizes all the scientific information known about the drug

The quantity known as ph measures:

the concentration of hydrogen ions in a solution

In 1921, the best way to measure glucose in blood was based on:

the final color of a mixture and some reagents

In the 1960s, the annual supply of insulin was limited by:

the number of cows and pigs slaughtered each year

James Collip, at the University of Toronto, developed a method to isolate insulin based upon:

the solubility of insulin in alcohol/water mixtures

The best treatment for diabetes about 1915 was known as:

the starvation diet

Several insulin analogies, like lispro, aspar, and glulisine, are produced by eli lilly. These insulin analogs differ from normal human insulin by:

they act quicker or slower after injection

Banting's method of isolating insulin involved a surgical procedure to tie off ducts in the pancrease, waitng several weeks, then moving the pancreas.

this method was used to produce insulin just a few times

The diabetes control and complications trial tested whether this method of treating diabetes was better than what patients had been doing:

tight control of glucose

An IACUC must have at least five members. One of these members must be a non-scientist.

true

Insulin that is secreted into your blood contains two chains: The A chain and the B chain.

true

The self-orienting millimeter scale applicator (SOMA) is a device that might allow oral delivery of insulin, or an insulin pill. The shape of the SOMA is based on the shape of which animal:

turtle

An insulin molecule in circulating in your bloodstream consists of:

two chains of amino acids linked together by disulfide bonds

Fred Banting performed his experiments on dogs at:

university of toronto

Professor Katrine Whiteson wants everyone to know that you can get affordable insulin at:

walmart

In 1921, how could you diagnose diabetes?

with a urine test

Today, most insulin is produced in a large factory by which types of organisms:

yeast or bacteria

The university of toronto licensed a patent on the production of insulin to eli lilly. The agreement allowed eli lilly to manufacture and sell insulin. In return, eli llilly would give the university of toronto:

5% of eli lilys net sales from the insulin

Glucose Oxidase was isolated from:

a fungus

Dick Berstein was one of the first people to:

a home blood glucose meters

The HbA1c test is named after:

a line of hemoglobin observed on a gel

Off label prescribing is when

a physician prescribes a drug to treat a condition that wa snot approved by the FDA

If a pateint with diabetes was seeing dr elliot joslin during the 1950's which is more likely to characterize the patient's treatment plan:

a strict diet and multiple injections of insulin each day

When Professor Katrine Whiteson was 11 years old, she learned how to control her diabetes by herself by going to:

a summer camp

What causes pernicious anemia?

a vitamin deficiancy

Axel Ullrich was the first person to insert the human insulin gene into a bacteria or clone the insulin gene. He obtained the human insulin gene that he lconed from:

a woman's insolinoma tumor that was surgically removed

Severe symptoms of hypoglycemia could be confused with:

alcoholic intoxication

Diabetes (type 1) is caused by:

an autoimmune reaction

A closed loop system for insulin delivery contains:

an insulin pump and a continuous blood glucose meter

An insulin pen differs from an insulin pump because

an insulin pump is attached to your body by tubing, but an insulin pen is not

A complete lack of vitamin A in a person's diet can lead to:

blindness

In 1921, picric acid was used as a:

both a common laboratory reagent and an explosive for artillery shells

In 1920 the company eli lilly was known for manufacturing:

capsules for drugs

The diabtetes control and complications trial monitored this complication that many diabetic pateints suffer:

damage to the retinas blood vessels

Afressa and exubera are two different insulin delivery systems. The two systems both

deliver insulin through the lungs

Which of the following was not a frequent complication from diabates before the diabetes control and complications trial:

dementia

X-ray crystallography can be used to

determine the three dimensional structure of a protein

The order of amino acids in a protein produced by your body is

determined by your DNA

the birth control drug nexplanon is implanted under the skin. nexplanon is an example of ___ ___ applied birth control.

drug delivery

Classic symptoms of diabetes include:

excessive urination

An IACUC isi the committee that decides whether to provide funding for scientists experiments.

false

Blood test are only for measuring the number of red blood cells a person has:

false

Hypoglycemia can be alleviated by injecting insulin.

false

Insulin from humans and cows are exactly alike.

false

Professor dorothy hodgkin was awarded the nobel prize in 1964 for deciphering the structure of insulin using the technique of xray crystallography

false

When insulin is injected uner the skin it has an immediate effect, lowering blood sugar levels withina few seconds.

false

One of the most common problems people who have lived with diabetes for decades have is with their:

feet

The loose control approach to managing a patient's diabetes can be characteried bu the following:

freedom to eat whatever they choose and a single dose of insulin per day