Ch 14 Lecture

According to the text, how much of the earth is covered by water?

70%

Which of the following antibacterial drugs does not Inhibit biosynthesis of proteins?

Bacitracin

These are 8 mm filter papers.

False

_________________________ , the first synthetic antimicrobial created, served as the foundation for the chemical development of a family of sulfa drugs.

Sulfanilamide

What is the name given to a secondary infection in a patient having a preexisting infection?

What is the name given to a secondary infection in a patient having a preexisting infection?

Which of the following antibacterial drugs does not cell wall biosynthesis?

diarylquinoline

This region is known as the "zone of inhibitors".

false

Which of the following is not a type of β-lactam antimicrobial?

glycopeptides

Which of the following combinations would most likely contribute to the development of a superinfection?

long-term use of broad-spectrum antimicrobials

Some drugs are dose dependent, meaning they are ___________ effective when administered in large doses to provide high levels for a short time at the site of infection.

more

The spectrum of activity of an antibacterial drug relates to diversity of targeted bacteria. A _____________ -spectrum antimicrobial targets only specific subsets of bacterial pathogens.

narrow

Which of the following routes of administration would be appropriate and convenient for home administration of an antimicrobial to treat a systemic infection?

oral

What is the name of a drug that it selectively kills or inhibits the growth of microbial targets while causing minimal or no harm to the host?

selective toxicity

Which of the following terms refers to the ability of an antimicrobial drug to harm the target microbe without harming the host?

selective toxicity

A scientist discovers that a soil bacterium he has been studying produces an antimicrobial that kills gram-negative bacteria. She isolates and purifies the antimicrobial compound, then chemically converts a chemical side chain to a hydroxyl group. When she tests the antimicrobial properties of this new version, she finds that this antimicrobial drug can now also kill gram-positive bacteria. The new antimicrobial drug with broad-spectrum activity is considered to be which of the following?

semisynthetic

Which of the following antimicrobial drugs is synthetic?

sulfanilamide

Which clinical situation would be appropriate for treatment with a narrow-spectrum antimicrobial drug?

treatment of strep throat caused by culture identified Streptococcus pyogenes

Tweezers must be sterilized in 70% ethanol.

true