Ch 23 Genomics
Which factors influence the amount of a specific protein that will be found in a cell? Multiple select question.
-Rate of degradation (turnover) of the protein -Level of mRNA produced from the gene -Rate of mRNA translation
The levels of a specific protein found in a cell depend on the amounts of _______ produced by transcription, the rate of mRNA _________ to synthesize the protein, and the _______ rate for the protein.
-mRNA Blank 2: translation Blank 3: turnover, degradation, or breakdown
The human genome has about ______ genes.
22,000
Which technique allows genome-wide analysis of gene expression?
DNA microarrays
Which of the following statements about the human genome is true? Multiple choice question.
It has approximately 20,000 genes, but only a subset of those genes are expressed in any given cell.
The transcriptome is the set of all ______ produced in one cell or a population of cells.
RNA Molecules
Which of the following statements about the genome and proteome is true?
The proteome of all species is usually much larger than the genome
What is the goal of functional genomics?
To understand the roles of genetic sequences in a given species
The mechanism by which different forms of mature mRNAs (messenger RNAs) are generated from the same pre-mRNA is called _________ _______ , which is also sometimes called exon shuffling.
alternative splicing
Chromatin immunoprecipitation (ChIP) is a technique that is used to ______.
analyze DNA-protein interactions
The field of genomics that aims to understand the roles of genetic (DNA, RNA, and amino acid) sequences in a given species is called _________ genomics.
functional
A gene that has been changed such that the normal function is altered is called a
gene knockout
Organisms that have a close evolutionary relationship tend to have _______
genes with similar DNA sequences
In a given species, the proteome is typically ______ the genome
larger than
Two-dimensional gel electrophoresis can Blank______.
separate a mixture of proteins within a cell extract
Homologous genes encode proteins that carry out ________
similar functions
The set of all RNA molecules that are transcribed in one cell or a population of cells is called the
transcriptome
