chemistry

metabolic syndrome fasting glucose criteria >/= 95 mg/dl >/= 105 mg/dl >/= 115 mg/dl >/= 100 mg/dl

>/= 100 mg/dl

metabolic syndrome blood pressure criteria >/= 130/85 >/= 125/80 >/= 135/90 >/= 140/95

>/= 130/85

metabolic syndrome triglycerides criteria >/= 155 mg/dl >/= 145 mg/dl >/= 150 mg/dl >/= 140 mg/dl

>/= 150 mg/dl

slow-acting barbiturate that effectively controls several types of seizures amphetamine digoxin dilantin phenobarbital

phenobarbital

the term pharmacokinetics BEST describes: what the drug does to the body concentration of drug at its sites of action what the body does to the drug concentration of the drug at the time of administering

what the body does to the drug

fluorometers are designed so that the path of the excitation light is at a right angle to the path of the emitted light. What is the purpose of this design? prevent loss of emitted light prevent loss of the excitation light focus emitted and excitation light upon the detector prevent incident light from striking the detector

prevent incident light from striking the detector

which of the following therapeutic drugs is a barbiturate and is used to control seizures? primidone cyclosporine digoxin disopyramide

primidone

A chemical reaction that is utilized by many different analytical methods involves: fluorometry glucose oxidase the reduction of NAD and NADH UV spectrophotometry

the reduction of NAD and NADH

TIBC (total iron binding capacity) is an indirect measurement of which of the following? ferritin hemoglobin ceruloplasmin transferrin

transferrin

which of the following is currently considered to be a good test for screening persons for hereditary hemochromatosis (HH) due to its sensitivity and specificity for iron overload? transferrin saturation liver biopsy phlebotomy serum iron alone

transferrin saturation

lipemia in a fasting serum sample is most likely caused by a increase in serum levels of cholesterol triglycerides protein phospholipids

triglycerides

which of the following are markers currently used to differentiate heart failure from lung disease? TnI and TnT BNP and NT-proBNP myoglobin and LD hs-CRP and homocysteine

BNP and NT-proBNP

which one of the following statements about serum ferritin is true? it is a sensitive indicator of iron deficiency elevation of serum ferritin is specific for hemochromatosis it is synonymous with transferrin it is a better test for bone marrow iron stores than a prussian blue stain of marrow particles

it is a sensitive indicator of iron deficiency

after complaining to her physician about persistent pelvic pain and abdominal pressure, Mrs. Smith had laboratory testing ordered. Since her physician would like to rule-out ovarian cancer, which of the following assays would be most helpful? CEA CA125 CA19-9 PSA

CA125

following a myocardial infraction which of the following enzymes will be the first to become elevated? CK LDH GGT ALT

CK

which of the following is true of C-reactive protein (CRP) when being used to assess the risk of cardiovascular disease? CRP levels are high in cardiovascular disease CRP levels are not affected by cardiovascular disease CRP levels are low in cardiovascular disease CRP has little clinical utility for assessing cardiovascular disease

CRP levels are high in cardiovascular disease

if CSF tubes numbered 1,2,and 3 CANNOT be analyzed within one hour, the correct procedure for the microbiology sample is to: refrigerate freeze leave at room temperature incubate in a 56 degree water bath

leave at room temperature

when evaluating a 2-hour glucose tolerance test report performed on a pregnant woman, which of the following results is considered NORMAL? less than 140 mg/dl less than 10 mg/dl greater than 153 mg/dl no change in glucose values

less than 140 mg/dl

what are the expected results of the laboratory markers in iron deficiency anemia? Decreased serum iron, increased transferrin, decreased ferritin, decreased percent saturation, and increased total iron binding capacity Decreased serum iron, decreased transferrin, decreased ferritin, variable percent saturation, and decreased total iron binding capacity Decreased serum iron, decreased transferrin, increased ferritin, decreased percent saturation, and decreased total iron binding capacity Decreased serum iron, normal or decreased transferrin, normal or increased ferritin, decreased percent saturation, and normal or decreased total iron binding capacity

Decreased serum iron, increased transferrin, decreased ferritin, decreased percent saturation, and increased total iron binding capacity

acute phase proteins generally fall into which category? Glycoproteins immunoglobulins lipoproteins microglobulins

Glycoproteins

which of the following sites is used most often for CSF collection? ventricles L1-L2 subarachnoid L3-L4

L3-L4

which medication is primarily used in the treatment of bipolar disorder? lithium imipramine amitriptyline doxepin

lithium

all of the following statements are true regarding the hepatic system and drug metabolism EXCEPT? changes in hepatic status will affect the concentration of circulating drugs eliminated. Hepatic disease states characterized by a loss of functional tissue may result in a longer drug half-life. Hepatic disease states characterized by a loss of functional tissue may result in slower rates of clearance. Metabolism of acetaminophen by the MFO system is altered by alcohol and makes it less toxic.

Metabolism of acetaminophen by the MFO system is altered by alcohol and makes it less toxic.

the pl of a protein is 9.2. This protein is placed in an electrical field where a buffer sets the pH at 10.0. Select the correct statement regarding the electrophoretic migration of this protein. This protein will have a net positive charge and will migrate to the anode, the positively charged electrode. This protein will have a net positive charge and will migrate toward the cathode, the negatively charged electrode. This protein will have a net negative charge and will migrate toward the anode, the positively charged electrode. This protein will have a net negative charge and will migrate to the cathode, the negatively charged electrode.

This protein will have a net negative charge and will migrate toward the anode, the positively charged electrode

metabolic acidosis is characterized by: increased pCO2 hyperventilation low pH high pH

low pH

metabolic syndrome HDL-cholesterol criteria men <35 mg/dl women <45 mg/dl men <40 mg/dl women <50 mg/dl men <45 mg/dl women <55 mg/dl men <30 mg/dl women <40 mg/dl

men <40 mg/dl women <50 mg/dl

metabolic syndrome abdominal obesity criteria men >/= 40 inches, women >/= 35 inches men >/= 35 inches, women >/= 40 inches men >/= 35 inches, women >/= 30 inches men >/= 45 inches, women >/= 40 inches

men >/= 40 inches, women >/= 35 inches

which of the following drug examples would be a good candidate for therapeutic drug monitoring(TDM)? a drug that is readily cleared a drug that has a narrow therapeutic window a drug that has a wide therapeutic window a drug that is used for short-term therapy

a drug that has a narrow therapeutic window

which of the following enzymes is associated with conditions affecting skeletal muscles? aldolase alkaline phosphatase (ALP) gamma-glutamyltransferase 5'-nucleotidase

aldolase

an automated method for measuring chloride which generates silver ions in the reaction is called amperometric-coulometric titration potentiometry chromatography polarography

amperometric-coulometric titration

which medication would be prescribed for narcolepsy? amphetamine digoxin dilantin phenobarbital

amphetamine

A physician needs to prescribe a drug to a patient but the drug has a narrow therapeutic window. He is concerned about possible toxic effects. To assess the upper concentration of such a drug, which time for drawing the specimen do you think makes the most sense? approximately one hour after an oral dose 2-4 hours after an IV injection of a drug before any drug is given right before the next dose of the drug is given

approximately one hour after an oral dose

the immunoassay procedure for serum hCG utilizes antisera against which subunit of hCG? alpha gamma epsilon beta

beta

In the condition kernicterus, the abnormal accumulation of bilirubin occurs in what tissue? brain liver kidney blood

brain

the parathyroid hormone (PTH) is important in the regulation of: iodine and bromine calcium and phosphate acid and alkaline phosphatase zinc and magnesium

calcium and phosphate

which of the following therapeutic drugs is an immunosuppressive and often used to suppress graft rejection of transplanted organs? primidone cyclosporine digoxin disopyramide

cyclosporine

Zinc deficiency in the elderly is often caused by: decreased intake and absorption decreased intake and excretion increased intake and excretion increased excretion and decreased absorption

decreased intake and absorption

In which of the following conditions would an increased serum osmolality be an expected finding? hyponatremia and dehydration increased arginine vasopressin hormone (AVP formerly ADH) secretion and in hyponatremia AVP and diabetes insipidus

dehydration and diabetes insipidus

A test for microalbuminuria is used most often to monitor patients with which of the following diseases or conditions? diabetes bacterial infection multiple myeloma hepatitis C

diabetes

prescribed for congestive heart failure amphetamine digoxin dilantin phenobarbital

digoxin

which of the following therapeutic drugs increases the force of myocardial muscle contraction? primidone cyclosporine digoxin disopyramide

digoxin

therapeutic agent prescribed for seizure disorders amphetamine digoxin dilantin phenobarbital

dilantin

which of the following therapeutic drugs is an antiarrhythmic agent? primidone cyclosporine digoxin disopyramide

disopyramide

What additional fraction would be seen if plasma rather than serum was subjected to electrophoresis? alpha-1 antitrypsin alpha-2 macroglobulin fibrinogen gamma globulins

fibrinogen

Which lipid abnormality is the MOST closely linked to heart disease? hypobetalipoproteinemia hypertriglyceridemia hypercholesterolemia abetalipoproteinemia

hypercholesterolemia

calcium and phosphorus levels were determined for a 4-year-old patient as follows: Ca 14 mg/dL phosphorus 1 mg/dL these results are most compatible with: hyperparathyroidism renal failure rickets hypervitaminosis

hyperparathyroidism

Tumor markers are especially valuable when used to: rule out cancer screen the general population for cancer monitor response to cancer therapy confirm other assays

monitor response to cancer therapy