Fate of pyruvate

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pyruvate dehydrogenase complex

A group of three enzymes that decarboxylates pyruvate, creating an acetyl group and carbon dioxide. The acetyl group is then attached to coenzyme A to produce acetyl-CoA, a substrate in the Krebs cycle. In the process, NAD+ is reduced to NADH. The pyruvate dehydrogenase complex is the second stage of cellular respiration.

pyruvate to acetyl-coA to citric acid cycle

Fate of pyruvate under aerobic conditions (Oxygen is available) in any cell type.

pyruvate to lactate/lactic acid

Fate of pyruvate under anaerobic conditions in eukaryotic cells (Oxygen is not available).

pyruvate to acetaldehyde to ethanol

Fate of pyruvate under anaerobic conditions in prokaryotic cells (oxygen is not available).

NADH

Under anaerobic conditions in eukaryotic cells, what coenzyme is used to convert pyruvate/pyruvic acid to lactate/lactic acid?

NADH

Under anaerobic conditions in prokaryotic cells, what coenzyme is used to convert acetaldehyde to ethanol?

CO2

What compound is released during the conversion of pyruvate/pyruvic acid to acetaldehyde in prokaryotes under aerobic conditions?

pyruvate decarboxylase

a homotetrameric enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide in the cytoplasm

alcohol dehydrogenase

second step of ethanolic fermentation: acetaldehyde + NADH(----?----) NAD+ + ethanol.

NAD+

under aerobic conditions, what coenzyme is used to convert pyruvate/pyruvic acid to Acetyl-coA?

lactate dehydrogenase

*Under anaerobic conditions Catalyzes the conversion of Pyruvate to Lactate consuming 1 NADH in the process


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