H2 Receptor Antagonists

Complete the cimetidine pharmacokinetics table by dragging the missing values to the correct cell.​

Onset: 15-60 minutes Peak: 1-2 hours Half-life: 2 hours Duration: 4-5 hours

Which statement(s) are correct concerning H2 receptor antagonists? (Select all that apply.)

*H2 blockers can be administered by IV *H2 receptor blockers inhibit gastric secretion *H2 blockers duration of action is 6-12 hours

A H2 receptor antagonist will be prescribed for a client. Which medications are H2 receptor antagonists? Select all that apply.

*famotidine *ranitidine

The H2 receptor antagonist dose in the older adult population should be 1._____________.

1. decreased due to slower renal function

Which statement about H2RA is correct? ​

They reduce hyperacidity in the stomach

Which routes can cimetidine be administered? Select all that apply. ​

*Intramuscular (IM) *Intravenous (IV) *By mouth (PO)

The client has an order for famotadine once daily. The nurse schedules the medications for which of the following times?

One (1) hour before or two (2) hours after medications

Patients with 1.___________ disease should use caution when taking H2 receptor antagonists.

Renal and hepatic

Which H2 receptor antagonist has the highest risk for drug interactions?

cimetidine

Which statement about H2 receptor antagonists administration is true?

H2 receptor antagonists can be administered at nigh

Which of the following statements about H2 receptor antagonists (H2RA) is correct?

H2RAs reduce hyperacidity by blocking receptors on specialized acid producing cells in the stomach.

Complete the cimetidine dosing information by dragging the missing values to the correct cell.

Heartburn -Dose: 200 mg -Frequency: Twice daily Gastroesophageal Reflux Disease (GERD) -Dose: 1600 mg; Divided -Frequency: 2-4 times daily

Which type of cells do H2 receptor antagonists bind to inhibit acid production?​

Parietal cells

A 75-year-old client has been admitted for a gastrointestinal bleed. The client is confused and disoriented after receiving several medications. Which medication can worsen confusion and disorientation for this client?

famotidine