Lesson 14

The rare cells within a cancer that are capable of indefinite self renewal and are responsible for maintaining the cancer

cancer stem cells

TF A mutation in even a single cancer critical gene is sufficient to convert a normal cell into a cancer cell

false

TF cells with one functional copy of a tumor suppressor gene will usually proliferate faster than normal cells

false

Describe cells that accumulate spontaneous genetic and epigenetic changes at an abnormally rapid rate

genetic instability

describes a tumor or tumor cell that can invade surrounding tissue or form tumors at other sites in the body

malignant

The neoplasm from which metastases were originally derived

primary tumor

a cancer arising from connective tissue or muscle cells

sarcomas

TF genes can be turned off in an inherited manner without any change in DNA sequence

true

general term for a normal gene in which a loss of function mutation can contribute to cancer

tumor suppresor genes

TF Oncogenes and tumor suppressor genes can both be detected by introducing fragmented DNA from cancer cells into suitable cell lines and isolating colonies that display cancerous properties

False