Lithium toxicity
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late signs
Coarse hand tremor ataxia (uncoordinated movement) GI upset Confusion Incoordination
LITHIUM
L-level of therapeutic affect is 0.5-1.5 I-indicate mania T-toxic level is 2-3 - N/V, diarrhea, tremors H-hyrdrate 2-3L of water/day I-increased UO and dry mouth U-uh oh; give Mannitol and Diamox if toxic s/s are present M-maintain Na intake of 2-3g/day
Early signs
Nausea/vomitting slurred speech muscle weakness diarrhea thirst polyuria