Osteoblasts vs osteoclasts
Secondary ossification
Appears after the first ossification center. In longs bones it appears in the epiphysis
Osteoblast
Calcium phosphate is absorbed into the matrix and hardens it
Osteoblast
Canaliculi extend out from the cells and connect to the other cells (gap junctions) so they can exchange nutrients and wastes
Osteoclast
Cells that originate from the same cells that make monocytes in the blood. Theses cells will dissolve and erode away mature bone tissue
Osteoblast
Eventually these cells become imbedded in the matrix they produce
Osteoclast
Produces calcium phosphate that digests the collagen of bone matrix
Osteoblast
Secrete of matrix as they lie on existing bone surfaces
Osteoclast
Secrets hydrochloric acid that will dissolve calcium phosphate in bone
Osteoclast
The cells they originate from are blood stem cells, hemopoietic cells
Primary ossification
The first area of the bone to start ossification. Occurs in the diaphysis
Osteoblast
The imbedded osteoblasts is now an osteocyte
Osteoclast
The regions of bone they dissolve away will be replaced as osteoblasts come to those site and produce to bone matrix
Osteoblast
The space is occupies is called a lucuna
Osteoclast
These cells are large and multinucleated
Osteoblast
This cell can no longer divide
Osteoblast
This matrix is a jelly like material made up of protein collagen fibers
