PHARMA
Bioavailability
Amount of drug that reaches the circulatory system after administration
diazepam and phenytoin
DOC: tonic clonic and status epilepticus
Posology
Study of dosages
atropine and scopolamine
belladonna alkaloids
Pharmcology
branch of medicine concerned with the uses, effects and modes of drugs
Pharmacodynamics
concerned with the effects of drugs and the mechanism of action
Cholinergic anti cholinergic diazepam
contraindicated drugs for glaucoma
Syrup of Ipecac
induces vomiting
Excretion
kidney
vit. A D E K
lipid/ fat soluble
metablism
liver and plasma
GABA
most common inhibitory neurotransmitter
Benzodiazepines
most commonly used in dentistry pedo/ adult
Chloral Hydrate
most commonly used in pediatric dentistry oral
nitrous oxide
most commonly used in pediatric pts
Pharmacokinetics
movement of drugs within the body
first pass effect
phenomenon of drug metabolism whereby the concentration of orally taken drugs us reduced
Activated Charcoal
prevents absorption of toxins into the body if the ingested substance is known to be affected by charcoal in the gastrointestinal (GI) tract
Absorption
process of drug uptake from the sure of administration towards the bloodstream
porphyrin
red tooth?
LA Analgesics Sedative hypnotics
safe for pregnant women
False
sedative hypnotics produces analgesia?
true
sedative hypnotics produces drug dependence
teratology
study of damage to fetus
Toxicology
study of drug's harmful effect
Adipocytes
temporary storage site of drugs
agonist
the drug that has affinity and intrinsic activity
Ultra short acting
very lipid soluble drug
vit b and c
water soluble vitamins
ADME
absorption, distribution, metabolism, excretion
Cumulation
accumulation of drug because it cannot be excreted by the body?
antagonist
affinity lang so it PREVENTS the effect
Benzodiapines
antagonist: flumazenil
narcotics
antagonist: naloxone
paton's rate theory
drug effect is proportional to the rate of the drug and receptor combine
clark's occupational theory
drug is proportional to the number of the receptors occupied
Distribution
happens at the plasma; albumin; lipid solubility (systemic distribution)
Absorption
happens at the small intestine