Pharmacology EDAPT: Antigout Drugs

Uric acid is produced as part of the metabolism process of

purines

What happens with uric acid to result in gout? Select all that apply.

too much not enough secreted a combination

What are the goals of gout treatment? Select all that apply.

prevent recurrent attacks decrease symptoms of an acute attack

Drag and drop to match the drug to its indication.

1. colchicine 2. allopurinol 3. probenecid 4. febuxostat

Drag and drop to match the drug to its correct dosage.

1. febuxostat 2 allopurinol 3. probenecid 4. colchicine

Drag and drop to match the drug to the mechanism of action.

1. probenecid 2. febuxostat 3. allopurinol 4. colchicine

What is the maximum daily dose of allopurinol?

800

Why is allopurinol considered safer than febuxostat?

Allopurinol has a lower risk for serious cardiovascular effects.

Drag and drop to sort the foods into high purine and low purine categories.

High: bacon, alcohol, organ meats, shellfish, turkey

What is involved in the pathophysiology of gout?

Inflammation resulting from intraarticular deposition of urate crystals

Which of the following drug class is the first line of drugs used to treat gout?

NSAIDS

Drag and drop to match the contraindication to the correct drug.

allopurinol: only in those with a known hypersensitivity to the drug colchicine: known hypersensitivity to it febuxostat: only in those with a known hypersensitivity to the drug probenecid: peptic ulcer disease

Too much uric acid in the blood is known as .

hyperuricemia