PhysioEx activity 4- blood typing

ABO and Rh antigens

- can cause incompatible blood type - present in the blood of a donor can react with antibodies in the blood of a transfusion recipient, resulting in clumping -cause the most vigorous and potentially fatal transfusion

agglutination

-result in a potentially life-threatening blood transfusion -results in red blood cell lysis -indicates the presence of an agglutinogen

which blood sample contained the universal recipient?

AB+

which blood type contained the rarest blood type

AB-

what antibody would be found in the plasma of blood sample 1?

Anti-B antibody

list the blood sample that represent people who could donate blood to a person with type B+ blood type

B+ (sample 2), B- (sample 6), O- (sample 4).

which blood sample contained the universal donar?

O-

which blood sample did not agglutinate with any of the antibodies tested? why?

Sample 4 did not agglutinate with any of the antibodies tested. This is because none of the antigens were present.

when transfusing an individual with blood that is compatible but not the same type, it is important to separate packed cells from the plasma and administer only the packed cells. why do you think this is done?

The plasma containst he antibodies that could react with the recipients antigens on RBCs

what is correct about blood type?

a person with type O blood has two alleles and has neither the type A nor type B antigen

Antibodies on Rh are innate or adaptive?

adaptive

red blood cell membranes have

agglutinations that specify that individuals blood type

Antigens bind to

antibodies

antigens

are present in all cells

ABO and Rh agglutination

cause the most vigorous and potentially fatal transfusion reaction

hemolytic disease

develops in Rh-positive fetuses of Rh-negative mothers

antibodies to the A and B antigens are

found performed in the blood plasma

Ab on A & B on RBC are innate or adaptive?

innate

to determine an individuals blood type, drops of the blood sample are mixed

separately with antiserum containing antibody antibodies that recognize either type A antigens, type B antigens, or Rh antigens

antibodies are

specific

Antigenic determinant (epitope)

specific region on the antigen that the antibody reacts with

why are individuals with AB+ blood known as universal recipients for blood transfusion

they have both A and B antigens on the surface of their RBCs, and their blood contain antibodies against A, B, or Rh