Quiz 5

How and where is the asymmetry of the phospholipid bilayers initially established?

It is initially established in the ER during lipid and protein synthesis.

________ are members of an integral membrane glycoprotein family that bind to specific sugar arrangements in oligosaccharides that project from the surfaces of other cells.

Selectins

What happens if misfolded proteins are generated in the ER at a faster rate than they can be exported to the cytoplasm?

They accumulate in the ER.

What are the two sites within a cell at which protein synthesis is generally thought to occur?

cytosolic surface of RER and free ribosomes

The tightest attachment between a cell and its extracellular matrix is seen at the site where an epithelial cell is attached to the underlying basement membrane. The specialized adhesive structure found at such a site is called a(n) ________.

hemidesmosome

Where are misfolded secretory proteins eventually destroyed?

in the cytosol (cytoplasm)

What determines the function of a cell's smooth endoplasmic reticulum?

its protein content

Filaments connected to the dense plaque underlying the membrane in a hemidesmosome course outward into the cytoplasm. These filaments are composed of the protein _____ and are best known as ______.

keratin, intermediate filaments

What is the arrangement of organelles in a secretory cell from the basal end to the apical end, an arrangement that reflects the flow of secretory products from synthesis to discharge? nucleus and RER - Golgi complex - SER - secretory vesicles SER - nucleus and RER - Golgi complex - secretory vesicles Golgi complex - nucleus and RER - SER - secretory vesicles secretory vesicles - nucleus and RER - SER - Golgi complex

nucleus and RER - SER - Golgi complex - secretory vesicles