W4

Amylo-1,6-glucosidase ("alpha-glucosidase")

A patient had large deposits of liver glycogen, which after an overnight fast had shorter than normal branches. This abnormality could be caused by a defective form of:

the primer on which new glycogen chains are initiated.

What is glycogenin?

pyridoxal phosphate (PLP)

Which one of the following cofactors requires glycogen phosphorylase?

Glucose 6-phosphate

Which one of the following is a common intermediate in the conversion of glycerol and lactate to glucose? A) pyruvate b) oxaloacetate c) malate d) Glucose 6-phosphate

Pyruvate to Oxaloacetate

Avidin, a 70-kd protein in egg white, has very high affinity for biotin, and is a highly specific inhibitor of biotin enzymes. Which of the following conversions would be blocked by the addition of avidin to a cell homogenate:

Requires 4 ATP + 2 GTP

The conversion of pyruvate to fructose 1,6-bisphosphate by the gluconeogenic pathway - requires?

More glucose 1-phosphate than glucose.

The degradation of glycogen normally produces which of the following?

Dietary would give 1 less ATP per glucose

What would the energy difference be between using glucose from a dietary source versus using glucose 1-phosphate from the glycogen stores?

It catalyzes addition of glucose residues to the nonreducing end of a glycogen chain by formation of alpha-1-4-bond

Which of the following is true of glycogen synthase?

E)

Which of the following statements is incorrect? A) Aerobically, oxidative decarboxylation of pyruvate forms acetate that enters the citric acid cycle. B) In anaerobic muscle, pyruvate is converted to lactate. C) In yeast growing anaerobically, pyruvate is converted to ethanol. D) Reduction of pyruvate to lactate regenerates a cofactor essential for glycolysis. E) Under anaerobic conditions pyruvate does not form because glycolysis does not occur.

Requires investment of 1 ATP+1UTP/glucose

Which one of the following statements is true for glycogen synthesis: