Week 2- The Immune System Pharmacology ATI Questions (Exam 1)

A nurse is teaching a guardian of a child about the recommended age range to receive the human papillomavirus (HPV) vaccine. Which of the following age ranges should the nurse include?

11 to 12 years old

A client is about to start therapy with topotecan to treat metastatic ovarian cancer. To minimize neutropenia, an adverse effect of topotecan, you should administer filgrastim at which of the following times?

24 hr after the topotecan infusion

You should instruct a client who is taking tamoxifen to treat breast cancer for watch for and report which of the following serious adverse effects of this drug?

Abnormal menstrual bleeding

A nurse is preparing to administer enfuvirtide to a client. Which of the following actions should the nurse plan to perform? (Select all that apply)

Administer the drug subcutaneously Roll the vial gently to reconstitute the solution Inject the solution at room temperature

A nurse should recognize that enfluvirtide can be prescribed to clients who have which of the following conditions?

Advanced HIV

A nurse is instructing a client how to self- administer enfuvirtide. Which of the following instructions should the nurse include?

Allow the vial to sit until the solution is completely clear and without particulates

A nurse is preparing to administer the measles, mumps, and rubella (MMR) vaccine to a child. The nurse should recognize that the MMR vaccine provides which of the following types of immunity?

Artificial active immunity

A client is about to start taking mercaptopurine to treat acute lymphocytic leukemia. You should instruct the client to watch for and report which of the following indications of an adverse effect of this drug?

Bruising

A nurse should recognize that maraviroc is used in the treatment of which of the following conditions?

Chemokine receptor 5 (CCR5) tropic HIV-1

A nurse is teaching a client who has a new prescription for imatinib to treat chronic myeloid leukemia. Which of the following instructions should the nurse include?

Clean fruits and vegetables thoroughly Weigh yourself daily Perform hand hygiene frequently Avoid grapefruit and grapefruit juice

You are assessing a client who is receiving imatnib to treat chronic myeloid leukemia. Which of the following findings might indicate an adverse reaction to this drug?

Crackles at lung bases Because this drug can cause fluid retention and pulmonary edema

A nurse is teaching a client who has a new diagnosis of breast cancer about the drug tamoxifen. The nurse should tell the client that which of the following conditions is a contraindication for taking tamoxifen?

Deep- vein thrombosis

A nurse is caring for a client who has a new prescription for intrathecal cytarabine therapy to treat meningeal leukemia. The nurse should inform the client that they will also receive which of the following drugs to reduce the risk of neurotoxicity?

Dexamethasone

When talking with the client about chemotherapy with doxorubicin, you explain the need for periodic diagnostic tests. The result of which of the following diagnostic tests or procedures requires monitoring?

ECG Because doxorubicin can cause cardiotoxicity

While administering trastuzumab IV to a client who has breast cancer, you should ensure that you have which of the following drug available to treat an adverse reaction to this drug?

Epinephrine

A client is about to start taking ritonavir to treat HIV-1 infection. Which of the following instructions should you include when talking with the client about taking this drug?

Expect periodic blood glucose testing Watch for and report jaundice Increase weight- bearing activity Expect periodic cholesterol testing

You should monitor this client for which of the following indications of an adverse reaction to cyclophosphamide?

Fever

A nurse preparing to administer paclitaxel IV to a client who has ovarian cancer. Which of the following actions should the nurse take?

Give the client an antihistamine Administer the drug through non- PVC tubing Use an in- line filter

Delaviridine therapeutic use:

HIV-1 infection

A nurse is teaching the guardian of a 4- month- old infant about recommended immunizations for the infant. Which of the following immunizations should the nurse include?

Haemophilus influenza type B vaccine (Hib)

A nurse is caring for a client who is prescribed zidovudine. Which of the following laboratory values should the nurse report to the provider?

Hemoglobin 7.1 g/dL (shouldn't be less than 7.5)

Your administering cyclophosphamide and mesna to a client. Mesna, a chemoprotective agent, helps prevent which adverse reactions to cyclophosphamide?

Hemorrhagic cystitis

A nurse is teaching a client about recommended immunizations. Which of the following immunizations should the nurse recommend the client receive starting at 50 years of age?

Herpes zoster vaccine

A nurse is caring for a client who has a new prescription for topotecan therapy to treat resistant, small- cell lung cancer. The nurse should advise the client against taking which of the following types of over-the-counter drugs while receiving the therapy?

Ibuprofen

You are about to adminster cisplatin to a client who has ovarian cancer. Before the infusion, you should take which of the following actions?

Infuse 1 to 2 L of IV fluid Administer an antiemetic Evaluate the client's hearing Determine the client's weight

A nurse is teaching a client about maraviroc. Which of the following instructions should the nurse include?

It is important to report any noticeable rash immediately as it might indicate an issue with your liver

A nurse is caring for a client who has a new prescription for maraviroc therapy. The nurse should instruct the client to report which of the following adverse effects?

Paresthesia Cough Jaundice Fever

A nurse is caring for a client who has a new prescription for cisplatin to treat testicular cancer. The nurse should instruct the client to report which of the following adverse effects?

Paresthesia Sore Throat Flank Pain Tinnitus

A nurse is caring for a client who has a new prescription for delavirdine to treat HIV-1. The nurse should instruct the client to report which of the following adverse reactions to the drug?

Rash

You should give the client which of the following instructions about chemotherapy with doxorubicin?

Report vaginal itching Expect red- tinged tears Use effective contraception Expect regrowth after hair loss

A nurse should recognize that raltegravir is used to treat clients who have which of the following conditions?

Resistant HIV

During IV administration of doxorubicin, the infusion site becomes swollen, red, and painful. Which of the following actions should you take?

Stop the IV infusion

A nurse is caring for a client who has a new prescription for ritonavir and zidovudine therapy to treat HIV-1. The nurse should inform the client that zidovudine is prescribed with ritonavir for which of the following reasons?

To prevent drug resistance

A nurse is considering drug therapy options for a client who has metastatic breast cancer that is postive for human epidermal growth factor receptor 2 (HER2). Which of the following drugs should the nurse expect the provider to prescribe?

Trastuzumab

A nurse is teaching a client who has a new prescription for mercaptopurine to treat leukemia. Which of the following instructions should the nurse include?

Use contraception if pregnancy is a risk Perform oral hygiene frequently Perform hand hygiene frequently Avoid activities that can cause injury

A nurse is caring for a client who is receiving vincristine to treat lung cancer. The nurse should monitor the client and recognize which of the following manifestations as an indication that the client is experiencing an adverse effect of the drug.

Weak hand grasps

A nurse is assessing a client following a trastuzumab infusion to treat metastatic breast cancer. Which of the following findings should the nurse recognize as an indication that the client is experiencing an adverse reaction to the drug?

Wheezing Dysrhythmias Hypotension Fever

Cystarabine therapeutic use:

acute myelocytic leukemia

Enfuvirtide therapeutic use:

advanced or resistant HIV disease

Tamoxifen therapeutic use:

estrogen- receptor- positive breast cancer

Carmustine therapeutic use:

gastrointestinal adenocarcinoma

Paclitaxel therapeutic use:

kaposi's sarcoma

Cyclophosphamide therapeutic use:

multiple myeloma

Flutamide therapeutic use:

prostate cancer

A nurse is teaching a client about immunizations. Which of the following information should the nurse include in the teaching?

You should receive a tetanus booster every 10 years

You are caring for a client who is pregnant and is HIV- positive. Which of the following drugs helps prevent the transfer of HIV to the fetus?

Zidovudine (Retrovir)