10 steps of DNA replication

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step 6

DNA polymerase starts adding nucleotides to 3- OH' end

step 1

DNA unwinds @ origin of replication

step 8

RNA primers removed by exonuclease activity

step 7

elongation of both lagging/leading strand

step 9

gap filled by DNA polymerase by adding dNTPs

step 2

helicase opens up DNA and makes replication fork

step 10

ligase seals 2 DNA fragments to make formation of phosphodiester bonds

step 5

primase synthesizes RNA primers, complementary to DNA strand

step 3

single strand bonding proteins coat DNA around replication fork to prevent rewinding DNA

step 4

topoisomerase binds @ region ahead of replication fork to prevent supercoiling


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