ASCP Board Exam - Blood Bank

What procedure utilizes leukapheresis to collect the buffy coat from whole blood? A. Photopheresis B. Plasmapheresis C. Therapeutic apheresis D. Erythrocytapheresis

A

Which of the following activities would require that a label be added to the blood label indicating the name and location of a second manufacturer? A. Irradiating a unit of red cells or platelets B. Shipping a unit to another facility C. Thawing a unit of plasma D. Receiving a unit from another facility

A

Which organism is MOST likely responsible for septic reactions associated with red blood cell transfusions? A. Yersinia enterocolitica B. Escherichia coli C. Enterobacter species D. Streptococcus species

A

Which of the following antigens are well developed on fetal cells? A. Lewis B. ABO C. Kell D. I

C

Which one of the following drugs/drug classes is the MOST COMMON cause of drug-induced immune hemolytic anemia? A. Levodopa B. Quinidine C. Cephalosporins D. Levofloxacin

C

Which adsorption technique removes cold (IgM) antibodies, particularly anti-I specificities? A. Cold autoadsorption B. Warm autoadsorption C. Differential (allogeneic) D. Rabbit erythrocyte stroma (RESt)

D

Which of the following statements is correct regarding blood bank adverse event reporting to the FDA? A. All patient deaths while being transfused must be reported to the FDA, even when it has been confirmed that the death was not related to the transfusion. B. When a transfusion reaction is the result of an error it must be reported to the FDA in writing. C. A transfusion-related death must be reported to the FDA within 24 hours of the patient's death. D. The initial notification to the FDA of a transfusion-related death must be made by fax, telephone, express mail, or electronically as soon as possible after the death is confirmed to be associated with the transfusion.

D

A mother's serologic results are shown above. Her newborn types as group A Rh positive with a (1+) positive direct antiglobulin test (DAT). Which of the following investigative tests would be most useful to resolve the cause of the positive DAT and should be done FIRST? A. Test an eluate prepared from newborn's red cells against an antibody identification panel by IAT. B. Test newborn's plasma against group A1 red cells and group O antibody screen cells by IAT. C. Test newborn's plasma against mother's red cells by IAT. D. Test newborn's plasma against father's red cells by IAT.

B

Which finding best distinguishes immune hemolytic anemia from other hemolytic anemias? A. Rouleaux B. Positive DAT C. Splenomegaly D. Increased erythrocyte count

B

On a quiet evening shift at a small hospital, you encounter a specimen with a positive antibody screen. As per your current laboratory protocol, you check for agglutination at the immediate spin phase of testing; and then again at the antihuman gloubulin (AHG) phase of 37°C. According to your laboratory guidelines, a single homozygous cell may be used to rule out an antibody. Based on the following 3-cell screen performed by tube, which of the following clinically significant antibodies are you unable to rule out? A. Anti-Fya, -D B. Anti-Lua, -Lea, -Fya, -C C. Anti-Lea, -Fya, -C D. Anti-Fya, -C, -Lub

D