Avascular Necrosis of Bone

Causes of Avascular Necrosis of Bone: The MCC is trauma/fracture, the second MCC is corticosteroids. What lifestyle habit can cause this?

Alcoholism --Again, random

Causes of Avascular Necrosis of Bone: The MCC is trauma/fracture, the second MCC is corticosteroids. What is Caisson disease and how can it cause this?

Caisson disease = Gas emboli --Gas emboli lodge in vessels, causing ischemia

Causes of Avascular Necrosis of Bone: The most common cause is trauma and fracture. What is the second most common cause?

Corticosteroids --Can't figure out the mechanism, but apparently its a popular question

Avascular Necrosis of Bone: The MCC is trauma/fracture, the second MCC is corticosteroids. Where is the most common location for this to occur?

Femoral head

Avascular Necrosis of Bone: This most often occurs at the femoral head. What vessel is occluded to cause this?

Fracture of the femoral neck will injure the medial circumflex femoral artery --Causes avascular necrosis of the femoral head

Avascular necrosis presents as pain with increased activity. Why does this occur?

Increasing activity increases the blood demand --Since blood is not supplied, pain develops

What is avascular (aseptic) necrosis of bone?

Ischemic necrosis of the bone and bone marrow

Avascular Necrosis of Bone: This can develop in the scaphoid bone. Why is it common in this bone?

Most frequently injured bone in the wrist Poor blood supply

What are the possible complications of avascular necrosis of bone? -Joints? -Weakened bones?

Osteoarthritis --Articular cartilage will be lost Fracture --Decreased blood supply makes the bone weak

What are the clinical features of avascular necrosis of bone? -Similar to claudication/angina

Pain with increased activity

Avascular Necrosis of Bone: The femoral head is the most common site. What is a common site of avascular necrosis in the wrist?

Scaphoid bone

Causes of Avascular Necrosis of Bone: The MCC is trauma/fracture, the second MCC is corticosteroids. What is a cause that can lead to dactylitis in the hands?

Sickle cell anemia --Sickled RBCs occlude blood flow --Dactylitis in the hands develops

Avascular Necrosis of Bone: What disease can lead to avascular necrosis of the digits?

Sickle cell disease

Avascular Necrosis of Bone: Sickle cell disease can lead to avascular necrosis of the digits. How does this occur?

Sickled RBCs occlude the blood flow --Dactylitis develops

Avascular necrosis of bone is ischemic necrosis of the bone and bone marrow. What is the most common cause?

Trauma and fracture --Injury cuts off the blood supply