Cancer Related Disorders (PREPU)
What statement provided by a nurse about immunosuppression following a solid organ transplant demonstrates understanding possible undesired results?
"When immunosuppression is inadequate, graft rejection reactions occur with solid organ transplantation."
A client is receiving idarubicin. What is the nurse's priority assessment?
Cardiac function
A child is prescribed an anthracycline drug. The nurse would teach the parents to observe for signs and symptoms of what adverse effect?
Cardiotoxicity
25s A patient is to receive doxorubicin as treatment for leukemia. The nurse would instruct the patient that the typical cycle would be repeated at which frequency?
Every 3 weeks
The nurse is explaining Rh factors to a client who will receive a blood transfusion. How should the nurse best describe histocompatibility antigens?
Genetically determined markers for self-cell identification
A nurse is addressing a group of nursing students about gamma globulins. What is the best response to the nursing students about the function of IgA?
Helpful in defense against invasion of microbes via nose, eyes, lungs, and intestines
A client's chemotherapeutic regimen includes procarbazine. What is the client's most likely diagnosis?
Hodgkin lymphoma
A nurse is administering an antineoplastic extravasation occurs. How can the nurse best prevent tissue damage caused by extravasation?
Inspect the site frequently for redness or swelling
A patient is diagnosed with ovarian cancer. Why is considered to be an aggressive form of cancer?
It is fed by the hormones produced by the ovaries.
Once a person has been exposed to a particular antigen and a repeat exposure occurs, what stimulates a quicker immune response?
Memory T cells
Which would the nurse identify as an antineoplastic antibiotic?
Mitomycin
A male client is informed that the latest tests indicate that his cancer has spread to his liver. The client receives capecitabine as part of his treatment regimen. What would the nurse expect the health care provider to do?
Monitor the client closely and repeat LFTs routinely.
How is the risk of renal impairment best minimized when foscarnet is administered?
Monitoring renal function two or three times weekly during induction
A nurse is administering an anti-inflammatory medication to a client who has severe rheumatoid arthritis. Which would the nurse question if ordered by the health care provider?
Oral anticoagulant
In which children or teenagers is the use of salicylates, particularly aspirin, contraindicated because their use appears to be associated with Reye syndrome?
Patients with chickenpox
When administering the fusion protein inhibitor enfuvirtide, the nurse should include which technique to assure the medication's continued effectiveness?
Regularly rotate the subcutaneous injection sites that are used.
The student nurse has learned that HIV is a retrovirus. Reverse transcriptase is the enzyme it contains. The student understands this enzyme when making which statement?
Reverse transcriptase is used to turn the RNA of the virus into DNA.
A client has been started on vincristine as part of treatment for cancer. What factor will the nurse need to assess with regard to interactions with this medication?
Sensory, motor, and perceptual functions
A nurse has administered a dose of a drug that is known to be highly protein bound. What are the implications of this characteristic?
The molecules of the drug that are bound to protein are inactive and do not affect body cells.
The nurse may be asked to administer which medications to a client to counteract the increase in uric acid and subsequent hyperuricemia resulting from the metabolic waste buildup from rapid tumor lysis?
allopurinol
A female patient is taking oral cyclophosphamide therapy for breast cancer. Because of possible adverse effects of the drug, the nurse will instruct the patient to:
drink a lot of water
A client with breast cancer is receiving goserelin (Zoladex). What aspect of the client's most recent laboratory results would suggest an adverse effect of this particular drug?
elevated serum calcium
Chemotherapeutic agents target cells at each phase of the cell cycle except:
the resting phase.
A 25-year-old female client is prescribed methotrexate to treat rheumatoid arthritis (RA). The nurse should teach the client to:
use an effective contraceptive