Cerebrospinal Fluid (CSF and Blood Brain Barrier (BBB)

What are the functions of CSF?

1. Buoyancy (Maintain brain shape) 2. Support and cushion brain 3. Environmental maintenance 4. Hormone transport

Which locations of the CNS have reduced or missing BBB?

1. Choroid plexus 2. Hypothalamus 3. Pineal gland

What are the four ventricles and what is their purpose?

1. Lateral ventricles (Left and right) 2. Third ventricle (Medial) 3. Fourth ventricle (Inferior Holds CSF

What is the BBB formed b?

Astrocytes

What colorless fluid circulates in the ventricles and subarchnoid space?

CSF

What is the capillary-rich membrane in the roofs of the four ventricles and consists of a layer of ependymal cells?

Choroid plexuses

Where is CSF made?

Choroid plexuses

What is the circulation of CSF?

Lateral ventricles ==> interventricular foramen ==> 3rd ventricle ==> cerebral aqueduct ==> 4th ventricle ==> lateral apertures or median aperture or central canal of spinal cord ==> subarachnoid space ==> excess CSF flow into arachnoid granulations ==> dural venous sinuses

What is the function of the BBB?

Maintains controlled environment around the neurons by preventing some molecules to not cross the brain capillaries