Chapter 21 Genomics

What is a sequence-tagged site?

A specific DNA sequence that can be amplified by PCR

How is genome sequencing likely to improve our understanding of human disease? Select all that apply

It may lead to the identification of human genes involved in disease. It can provide information about genes found in pathogens that infect humans.

Which represent outcomes of using the RNA-sequencing (RNA-seq) method? Select all that apply

Patterns of RNA splicing found in a particular cell type can be determined. Genes that are expressed in a specific cell type can be identified.

What is high-throughput sequencing?

The ability to rapidly sequence large amounts of DNA

Why have agriculturally important species been selected for genome sequencing?

Understanding their genomes may aid in the development of new strains with improved traits.

The genomes of certain agriculturally important species have been sequenced. The purpose of selecting these species for sequencing is that knowledge of their genomes may lead to Select all that apply

development of plant species with improved traits. development of new strains of livestock.

One of the advantages of shotgun DNA sequencing compared to other methods is that it

does not require extensive mapping

As an outcome of the RNA-sequencing (RNA-Seq) method, a cDNA sequence was shown to align with a specific region within the genome. This means that the sequence at that region is a(n)

gene that is expressed.

The tendency of different microsatellites to be transmitted together to the same offspring indicates that the microsatellites are

linked