Chapter 4 IGGY

A nurse obtains health histories when admitting clients to a medical-surgical unit. With which client should the nurse discuss predisposition genetic testing? a. Middle-aged woman whose mother died at age 48 of breast cancer b. Young man who has all the symptoms of rheumatoid arthritis c. Pregnant woman whose father has sickle cell disease d. Middle-aged man of Eastern European Jewish ancestry

ANS: A

A health care provider prescribes genetic testing for a client who has a family history of colorectal cancer. Which action should the nurse take before scheduling the client for the procedure? a. Confirm that informed consent was obtained and placed on the client's chart. b. Provide genetic counseling to the client and the client's family members. c. Assess if the client is prepared for the risk of psychological side effects. d. Respect the client's right not to share the results of the genetic test.

A

A nurse cares for a pregnant client who has a family history of sickle cell disease. The client is unsure if she wants to participate in genetic testing. What action should the nurse take? a. Provide information about the risks and benefits of genetic testing. b. Empathize with the client and share a personal story about a hereditary disorder. c. Teach the client that early detection can minimize transmission to the fetus. d. Advocate for the client and her baby by encouraging genetic testing.

A

A nurse consults a genetic counselor for a client whose mother has Huntington disease and is considering genetic testing. The client states, "I know I want this test. Why do I need to see a counselor?" How should the nurse respond? a. "The advanced practice nurse will advise you on whether you should have children or adopt." b. "Genetic testing can be a stressful experience. Counseling can provide support and education throughout the process." c. "There is no cure for this disease. The counselor will determine if there is any benefit to genetic testing." d. "Genetic testing is expensive. The counselor will advocate for you and help you obtain financial support."

B

A client is typed and crossmatched for a unit of blood. Which statement by the nurse indicates a need for further genetic education? a. "Blood type is formed from three gene alleles: A, B, and O." b. "Each blood type allele is inherited from the mother or the father." c. "If the client's blood type is AB, then the client is homozygous for that trait." d. "If the client has a dominant and a recessive blood type allele, only the dominant will be expressed."

C

A nurse cares for a client who has a specific mutation in the a1AT (alpha1-antitrypsin) gene. Which action should the nurse take? a. Teach the client to perform monthly breast self-examinations and schedule an annual mammogram. b. Support the client when she shares test results and encourages family members to be screened for cancer. c. Advise the client to limit exposure to secondhand smoke and other respiratory irritants. d. Obtain a complete health history to identify other genetic problems associated with this gene mutation.

C

A nurse cares for a client who recently completed genetic testing and received a negative result. The client states, "I feel guilty because so many of my family members are carriers of this disease and I am not." How should the nurse respond? a. "You are not genetically predisposed for this disease but you could still become ill. Let's discuss a plan for prevention." b. "Since many of your family members are carriers, you should undergo further testing to verify the results are accurate." c. "We usually encourage clients to participate in counseling after receiving test results. Can I arrange this for you?" d. "It is normal to feel this way. I think you should share this news with your family so that they can support you."

C

A nurse is educating a client about genetic screening. The client asks why red-green color blindness, an X-linked recessive disorder noted in some of her family members, is expressed more frequently in males than females. How should the nurse respond? a. "Females have a decreased penetrance rate for this gene mutation and are therefore less likely to express the trait." b. "Females have two X chromosomes and one is always inactive. This inactivity decreases the effect of the gene." c. "The incidence of X-linked recessive disorders is higher in males because they do not have a second X chromosome to balance expression of the gene." d. "Males have only one X chromosome, which allows the X-linked recessive disorder to be transmitted from father to son."

C

A client who tests positive for a mutation in the BRCA1 gene allele asks a nurse to be present when she discloses this information to her adult daughter. How should the nurse respond? a. "I will request a genetic counselor who is more qualified to be present for this conversation." b. "The test results can be confusing; I will help you interpret them for your daughter." c. "Are you sure you want to share this information with your daughter, who may not test positive for this gene mutation?" d. "This conversation may be difficult for both of you; I will be there to provide support."

D

A nurse cares for an adult client who has received genetic testing. The client's mother asks to receive the results of her daughter's genetic tests. Which action should the nurse take? a. Obtain a signed consent from the client allowing test results to be released to the mother. b. Invite the mother and other family members to participate in genetic counseling with the client. c. Encourage the mother to undergo genetic testing to determine if she has the same risks as her child. d. Direct the mother to speak with the client and support the client's decision to share or not share the results.

D

A nurse completes pedigree charts for clients at a community health center. Which diagnosis should the nurse refer for carrier genetic testing? (Select all that apply.) a. Huntington disease b. Breast cancer c. Hemophilia d. Colorectal cancer e. Sickle cell disease f. Cystic fibrosis

ANS: C, E, F

A nurse cares for a client who recently completed genetic testing that revealed that she has a BRCA1 gene mutation. Which actions should the nurse take next? (Select all that apply.) a. Discuss potential risks for other members of her family. b. Assist the client to make a plan for prevention and risk reduction. c. Disclose the information to the medical insurance company. d. Recommend the client complete weekly breast self-examinations. e. Assess the client's response to the test results. f. Encourage support by sharing the results with family members

ANS: A, B, E

A nurse teaches clients about patterns of inheritance for genetic disorders among adults. Which disorders have an autosomal dominant pattern of inheritance? (Select all that apply.) a. Breast cancer b. Alzheimer's disease c. Hemophilia d. Huntington disease e. Marfan syndrome f. Cystic fibrosis

ANS: A, D, E

A nurse cares for a client who has a genetic mutation that increases the risk for colon cancer. The client states that he does not want any family to know about this result. How should the nurse respond? a. "It is required by law that you inform your siblings and children about this result so that they also can be tested and monitored for colon cancer." b. "It is not necessary to tell your siblings because they are adults, but you should tell your children so that they can be tested before they decide to have children of their own." c. "It is not required that you tell anyone about this result. However, your siblings and children may also be at risk for colon cancer and this information might help them." d. "It is your decision to determine with whom, if anyone, you discuss this test result. However, you may be held liable if you withhold this information and a family member gets colon cancer."

ANS: C

A nurse cares for a client of Asian descent who is prescribed warfarin (Coumadin). What action should the nurse perform first? a. Schedule an international normalized ratio (INR) test to be completed each day. b. Initiate fall precautions and strict activity limitations. c. Teach the client about bleeding precautions, including frequent checks for any bruising. d. Confirm the prescription starts warfarin at a lower-than-normal dose.

ANS: D