Clinical Pharmacology Dosage Calculation

1 kilograms

1000 grams

1 quart

1000 mL

Question 10 The PCP has ordered bumetanide (Bumex) 1 mg IV ASAP. You have available: bumetanide (Bumex) 0.25 mg per mL. How many mL do you administer? _____________ mL

4 mL 0.25 mg / 1 mL = 1 mg / x mL 1 = 0.25x x = 4 mL

2.2 lbs

1 kg

1 milligram

1000 micrograms

1 gram

1000 milligrams

1 Tablespoon

15 mL

Question 1 The PCP has ordered ceftriaxone (Rocephin) 125 mg IM STAT. You have available: ceftriaxone (Rocephin) 500 mg per 10 mL. How many mL do you administer? _____________ mL

2.5 mL 500 mg / 10 mL = 125 mg / x mL 1250 = 500x x = 2.5 mL

Question 7 The PCP has ordered acetaminophen (Tylenol) 650 mg oral solution by NG tube. You have available: acetaminophen (Tylenol) 500 mg per 15 mL. How many mL do you administer? _____________ mL

19.5 mL 500 mg / 15 mL = 650 mg / x mL 9750 = 500x x = 19.5 mL

1 inch

2.5 cm

Question 8 A patient's blood glucose is 430 at 7am. He is scheduled to receive 10 units of Humulin NPH and sliding scale Humulin R according to the following formula: ( Blood Glucose - 100)/ 30 = # of units of Humulin R. How many total units of insulin will you administer? _____________ units

21 units (430 - 100) / 30 = 11 units of R 11 units R + 10 units NPH = 21 total units

1 ounce

30 mL

1 teaspoon

5 mL

1 pint

500 mL

Question 3 The PCP has ordered promethazine (Phenergan) 25 mg IM. You have available: promethazine (Phenergan) labeled 100 mg per mL. How many mL will you administer? _____________ mL

0.25 mL 100 mg / 1 mL = 25 mg / x mL 25 = 100x x = 0.25 mL

Question 4 The PCP has ordered an infusion of D5W 500 mL containing 20,000 units of heparin at 45 mL/hr. How many units per hour will the nurse infuse for the correct dosage? _____________ units/hour

1,800 units/hour 20000 units / 500 mL = 40 units/mL 40 units / 1 mL = x units / 45 mL x = 1800 units, so 1800 units/hour

Question 6 The PCP has ordered dexamethasone (Decadron) 9 mg IM STAT. You have available: dexamethasone (Decadron) 4 mg per mL. How many mL do you administer? _____________ mL

2.3 mL 4 mg / 1 mL = 9 mg / x mL 9 = 4x x = 2.25, so x = 2.3 mL

Question 5 The PCP has ordered Epivir 0.45 g PO every day. You have available: Epivir tablets labeled 150 mg. How many tablets do you administer? _____________ tablets

3 tablets 0.45 grams = 450 mg 150 mg / 1 tablet = 450 mg / x tablets 450 = 150x x = 3 tablets

1 oz

30 mL

Question 9 The PCP has ordered Gantrinsin 150 mg/kg by mouth divided into 3 doses over 24 hours for a urinary tract infection. The child's weight is 132 lbs. How many mg per dose will you give? _____________ mg

3000 mg 132 lbs = 60 kg 150 mg * 60 kg = 9000 mg / day 9000 mg / 3 doses = 3000 mg / dose

Question 2 The PCP has ordered 1 L of D5W NS to infuse at 125 mL/hr. The administration set delivers 15 gtt/mL. Calculate the IV flow rate in gtt/min. _____________ gtt/min

31 gtt/mL 125 mL / 60 mins = x mL / 1 min 125 = 60x x = 2.80333333 mL/min 15 gtt / 1 mL = x gtt / 2.80333333 mL x = 31.25, so x 31 gtt/min