CU patho Metabolic

A pancreatitis patient is admitted with weight loss, nausea, and vomiting. To maintain nutrition, the physician orders parental nutrition to be started. Knowing that a major side effect of parenteral nutrition is a hyperosmolar hyperglycemic state, the nurse should assess the patient for which clinical manifestations (listed below)?

Dry lips, excess urine output, and seizures.

Infections are common in people with diabetes. Which infection is thought to be related to a neurogenic bladder?

Pyelonephritis

A 15 year-old boy with type 1 diabetes is exasperated by his regimen of blood sugar monitoring and insulin administration, and has told his mother that he wants to scale both back. Which of the following responses by his mother is most accurate?

"Even though it's hard to do, you need to continue so you don't go blind or need a kidney transplant down the road."

A three year-old girl has just been diagnosed with type 1A diabetes. Her parents are currently receiving education from the diabetes education nurse. How can the nurse best explain to the parents the etiology (cause) of their daughter's diabetes?

"The problem that underlies her diabetes is that her own body has destroyed the cells in her pancreas that produce insulin."

The nurse is reviewing assessment data on four clients. Select the *client at highest risk for developing type 2 diabetes*.

A 45-year-old obese female with a sedentary lifestyle

A nurse is evaluating patients for the risk of developing type 2 diabetes. Which of the following patients has the highest risk?

A 45-year-old obese woman with a sedentary lifestyle

A 48-year-old male client diagnosed with type 2 diabetes presents with the following: • Blood glucose level of 46 mg/dL • Very lethargic • Has cool, clammy skin.

Administer injectable glucagon

Hypoglycemia has a sudden onset with a progression of symptoms. What are the signs and symptoms of hypoglycemia?

Altered cerebral function and headache

While reviewing the role of glucagon in regards to regulation of blood glucose, the nurse knows which of the following situations could lead to an inhibition of glucagon release?

An increase in glucose levels.

The pancreas is an endocrine organ that is composed of the acini and the islets of Langerhans. The islets of Langerhans have alpha, beta, and delta cells as well as the PP cell. *Which cells secrete insulin*?

Beta cells

The nurse and nursing student are caring for a client undergoing a severe stressor with release of epinephrine into the bloodstream. Which of these effects on blood glucose levels does the nurse teach the student epinephrine will cause?

Blood glucose will elevate.

A client with diabetes mellitus has sudden onset of slurred speech, incoordination, and cool, clammy skin. What will the nurse do first?

Check blood glucose

A client with diabetes mellitus reports morning hyperglycemia for several days. What action should taken?

Check blood glucose at 2 AM

Diabetics are hospitalized for a number of reasons. What is the most common complication of diabetes requiring hospitalization?

Foot problems

The family of a client in the hospital with diabetes mellitus out of control asks the nurse to explain the client's recent weight loss while eating more than usual. How will the nurse respond?

Glucose is unused without insulin, so body fats are used for energy.

Which of the following statements best describes an aspect of the normal process of glucose metabolism?

Glucose that exceeds metabolic needs is converted and stored by the liver.

A patient has been admitted with diabetic ketoacidosis. The Emergency Department starts an IV to improve circulatory volume. If there is a sudden change in extracellular fluid osmolality which results in a too rapid blood glucose lowering, the nurse will likely observe which of the following clinical manifestations?

Headaches, dizziness, change in level of consciousness.

During periods of fasting and starvation, the glucocorticoid and other corticosteroid hormones are critical for survival because of their stimulation of gluconeogenesis by the liver. When the glucocorticoid hormones remain elevated for extended periods of time, what can occur?

Hyperglycemia

A 30-year-old male who manages his type 1 diabetes with glyburide presents at the emergency room complaining of headache, confusion, and tachycardia. He has come from a party at which he drank two beers to celebrate running his first half-marathon. Which of the following is likely to be the cause of his complaints?

Hypoglycemia

A man is brought into the emergency department by paramedics who state that the client passed out on the street. The man smells of alcohol, and when roused says he has not eaten since yesterday. He is wearing a medic alert bracelet that says he is a diabetic. What would the nurse suspect as a diagnosis?

Hypoglycemia

While trying to explain the physiology behind type 2 diabetes to a group of nursing students, the instructor will mention which of the following accurate information?

In skeletal muscle, insulin resistance prompts decreased uptake of glucose. Following meals (postprandial), glucose levels are higher due to diminished efficiency of glucose clearance.

The diagnosis of type 1 diabetes would be confirmed by:

Insulin is not available for use by the body.

A client is admitted to the emergency department and diagnosed with diabetic ketoacidosis (DKA). The client would most likely manifest:

Ketosis

Diabetics are at higher risk than are the majority of the population for injury to organ systems in the body. Which organs are most at risk?

Kidneys and eyes

A client with diabetic retinopathy develops a retinal bleed and asks the nurse, "How can I prevent this from happening again?" What response provides the most effective information?

Maintain healthy blood pressure and blood sugar levels.

A client with diabetes mellitus arrives at the hospital with a blood glucose level of 639 mg/dl. What assessment data would indicate type 2 diabetes mellitus rather than type 1?

Negative ketones in urine

Secondary diabetes occurs because of disorders that produce hyperglycemia by stimulating the hepatic production of glucose or decrease the cellular use of glucose. Which disorders can be causes of secondary diabetes?

Pheochromocytoma and Cushing syndrome

A client has been experiencing elevated blood glucose levels. The nurse anticipates that the client assessment data would include:

Polydipsia

What are the *hallmark signs of diabetes mellitus*?

Polyuria, polydipsia, and polyphagia

The nurse is caring for a client diagnosed with diabetes mellitus who is reporting burning pain of his feet. The nurse would interpret this as:

Somatic neuropathy

The nurse is teaching a client with diabetes and the family about the *signs and symptoms of hypoglycemia*. The client asks what produces signs and symptoms of headache, disturbed behavior, coma, and seizures. The best response would be:

The brain relies on blood glucose as its *main energy source*.

A client is managing his diabetes with exercise and diet. The health care provider reviews the client's most recent lab results: fasting blood sugar level at 80 mg/dL and a hemoglobin A1C of 5%. Select the response that best identifies the client.

The client is achieving normal glycemic control.

A client with type 1 diabetes mellitus wishes to stop taking insulin injections. What option is appropriate?

Using an insulin infusion pump

Which clients with diabetes mellitus would the nurse anticipate to have persistent elevation of blood glucose levels? *Select all that apply*

• A client with high anxiety • A client with COPD taking steroids • A client with a leg fracture

A patient is evaluated for diabetes. Which of the following signs and symptoms would the nurse identify as indications of increased blood glucose levels? *Select all that apply*

• Blurred vision • Thirst • Fatigue • Skin infections

A patient is diagnosed with metabolic syndrome. Frequent concomitants of this syndrome include which of the following? *Select all that apply*

• Body mass index (BMI) greater than 30 • Elevated fasting blood glucose (FBG) • Coronary artery disease • Hypertriglyceridemia

A diabetic client presents to the clinic. He is concerned his lower legs are "feeling funny." Which of the following assessment findings lead the health care provider to suspect the client may have developed somatic neuropathy? *Select all that apply*

• Both legs appear to be the same as far as numbness is involved. • Bilateral cool ankles and feet. • With eyes closed, the client cannot identify where the HCP is touching his feet.

A patient with diabetes has been injured. The nurse will tell the patient that healing of the injury may be delayed due to which of the following diabetic complications? *Select all that apply*

• Chronic neuropathies • Vascular impairment

For which conditions is diabetes mellitus a risk factor? *Select all that apply*

• Coronary artery disease • Cerebrovascular accident • Chronic kidney disease

A woman with poorly controlled type 1 diabetes has been admitted to a hospital unit for the treatment of ketoacidosis. Place the following events in the pathophysiology of ketoacidosis in the correct chronological order. Use all the options.

• Decrease in pH • Breakdown of triglycerides • Low serum insulin levels • Ketone production by the liver • Production of fatty acids and glycerol

Type 2 diabetes is caused by metabolic abnormalities in the presence of insulin. What are these metabolic abnormalities? (*Select all that apply*.)

• Deranged secretion of insulin • Insulin resistance • Increased glucose production by the liver

A patient hospitalized with type 1 diabetes has been administered a scheduled dose of regular insulin. Which of the following are processes of insulin? *Select all that apply*

• Fat storage • Glucose uptake by muscle and adipose tissue • Protein synthesis

Which complications may be experienced by a client with diabetic neuropathies? *Select all that apply*

• Foot ulcers • Gastroparesis • Erectile dysfunction • Urinary retention

A young adult has been experiencing some extreme fatigue, changes in vision and unexpected weight loss. At the health clinic, the healthcare provider is assessing for hyperglycemia. Which would be considered the most commonly identifiable signs/symptoms of diabetes? *Select all that apply*

• Frequent thirst • Excess urination • Ravaging hunger

Hormones that counteract insulin's storage function when regulating blood glucose during times when glucose intake is limited or glucose stores are depleted are called counterregulatory hormones. What are the counterregulatory hormones? (*Select all that apply*.)

• Glucocorticoids • Growth hormone • Catecholamines • Glucagon

A woman in her 28th week of pregnancy develops gestational diabetes mellitus and has persistent elevated blood glucose when using the diet plan. What medications are appropriate? *Select all that apply*

• Glyburide • Insulin

A 54 year-old male who lives alone and has poorly controlled type 1 diabetes has been admitted to hospital for treatment of sepsis resulting from a chronic foot ulcer. Which of the other findings from the man's admission assessment and history would his care team be likely to attribute to his diabetes? *Select all that apply*

• The client complains of bloating after eating a meal, and states that he is unable to eat much food at any one sitting. • He states that his bowel movements are almost always loose. • The client states that he has been unable to maintain an erection in recent years.

A client with type 2 diabetes has routine lab work, which reveals elevated free fatty acids (FFA). The client asks, "Why is this significant?" The most accurate response would be: Select all that apply.

• This may increase the amount of triglyceride (a form of fat) stored in your liver or around your heart. • Your pancreas is affected by increased fat (lipotoxicity), which causes beta cell dysfunction, leading to the need for insulin.

Following an oral glucose tolerance, a 36 year-old mother of 4 has been diagnosed with gestational diabetes mellitus (GDM), a problem that was not present in any of her previous pregnancies. What should her primary care provider tell her about this new health problem?

"Your baby could become too large or have low blood sugars if we're not vigilant about controlling your sugars."

A 30 year-old man with a diagnosis of type 1 diabetes is aware of the multiple effects that insulin has on his metabolism. Which of the following physiological processes are actions of insulin? *Select all that apply*

• Facilitating triglyceride synthesis from glucose in fat cells • Inhibiting protein breakdown • Promoting glucose uptake by target cells.

A patient is diagnosed with hyperglycemic hyperosmolar state (HHS). Which of the following factors contribute to the severe hyperglycemia that precipitates HHS? *Select all that apply*

• Hyperglucagonemia • Glycosuria and dehydration • Hepatic glycogenolysis • Insulin deficiency

A client is brought to the emergency department with a suspected diagnosis of DKA (diabetic ketoacidosis). Select the assessment/diagnostic data to confirm the diagnosis. *Select all that apply*

• Low serum bicarbonate • Positive urine ketones

A client admitted to the hospital with elevated blood glucose is diagnosed with type 2 diabetes mellitus. What characteristics commonly differentiate type 2 diabetes mellitus from type 1 diabetes mellitus? *Select all that apply*

• Onset after age 35 • Overweight

A 60 year-old man has long managed his type 1 diabetes effectively with a combination of vigilant blood sugar monitoring, subcutaneous insulin administration and conscientious eating habits. This morning, however, his wife has noted that he appears pale and clammy and appears to be in a stupor, though he is responsive. She suspects that he has made an error in his insulin administration and that he is experiencing a hypoglycemic episode. Which of the following actions should be the wife's first choice?

Administration of 15 to 20 g of glucose in a concentrated carbohydrate source.

A client admitted to the hospital with elevated blood glucose is diagnosed with type 1 diabetes mellitus. What characteristics commonly differentiate type 1 diabetes mellitus from type 2 diabetes mellitus? *Select all that apply*

• Onset before age 20 • Autoimmune beta cell damage • Abrupt onset of symptoms

A client with a history of diabetes presents to the emergency department following several days of polyuria and polydipsia with nausea/vomiting. On admission, the client labs show a blood glucose level of 480 mg/dL and bicarbonate level of 7.8 mEq/dL. The nurse suspects the client has diabetic ketoacidosis (DKA). The priority intervention should include:

Begin a loading dose of IV regular insulin followed by a continuous insulin infusion.

When caring for the client with diabetic ketoacidosis, the nurse recognizes that fatty acids and ketones may be used for energy by most organs. Which of these organs does the nurse recognize is *reliant on glucose as the major energy source*?

Brain

A pregnant client asks the nurse if she is at risk for developing gestational diabetes. The nurse reviews the risk factors with the client. The most important information for the nurse to provide would be: *Select all that apply*

• Polycystic ovary disease • Glycosuria • Severe obesity

Which of the following criteria about insulin would prompt a diagnosis of type 1 diabetes?

Complete failure of insulin secretion

The nurse knows that increased blood glucose levels will pull water out of cells and result in which of the following? *Select all that apply*

• Polydipsia • Polyuria

Select the most common symptoms of diabetes. *Select all that apply*

• Polydipsia • Polyuria • Polyphagia

A client presents to the emergency room with fatigue, weakness, dehydration and thirst. What additional symptoms would correlate with a diagnosis of type 1 diabetes mellitus? *Select all that apply*

• Recent weight loss • Polyuria • Blurred vision

A diabetic patient's most recent blood work indicated a decreased glomerular filtration rate, and urine testing revealed microalbuminuria. Which of the following self-care measures should the nurse suggest to the patient? *Select all that apply*

• Stop smoking. • Maintain systolic pressure below 130 mm Hg. • Restrict protein consumption.

A 15-year-old who has just been diagnosed with type 1 diabetes says she read on the Internet that diabetes is the leading cause of acquired blindness among Americans. She asks you if she will lose her sight. In addition to explaining that new treatment technologies are being worked on every day, which of the following would be the most appropriate response?

Explain that almost all people with type 1 diabetes do experience some degree of vision loss.

A 40 year-old man who is morbidly obese and leads a sedentary lifestyle has recently been diagnosed with type 2 diabetes. Which of the following aspects of the man's obesity likely contributed to his new health problem?

Free fatty acids contribute to problems such as beta cell dysfunction and insulin resistance.