Events at a Cholinergic Synapse
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Event 5
Synaptic knob reabsorbes choline from the synaptic cleft and uses it to synthesize new molecules of ACh.
Event 3
ACh binds to receptors, depolarizes postsynaptic membrane.
Event 4
ACh is removed by AChE; AChE breaks ACh into acetate and choline.
Event 1
Action potential arrives, depolarizes synaptic terminal.
Event 2
Calcium ions enter synaptic terminal, trigger exocytosis of ACh.
