FACTORS STUDIED

holandric gene

a gene located on the Y chromosome in XY species

hemophilia

a hereditary condition for bleeding due to the inability to clot properly

Rh factor

an inherited protein found on the surface of the red blood cell membrane

The blood type AB is an example of __ dominance.

co

In the ABO series, the gene for blood type O is ___________________, while A and B are _________________ genes, and AB is __________________________.

recessivedominantcodominant

Hemophilia is a condition where the blood clotting action is dangerously high. True or False

False

In considering sex-linked inheritance, both sexes are equally susceptible to the manifestation of the trait. True or False

False

In sex-linked inheritance, females are most susceptible because they have only one X chromosome. Therefore, whichever gene is present, be it dominant or recessive, it is expressed. The male has two X chromosomes, and in order to be expressed, both genes must be recessive. True or False

False

The factors that are responsible for the ABO blood type, or the Rh, are located on the surface of the ___________

erythrocyte

A female can be susceptible to expressing hemophilia. True or False

True

The blood type trait is controlled by more than two alleles for a given gene and therefore is called multiple alleles. True or False

True

What would be a female bleeder's genotype? (Let XB stand for the normal condition for clotting and Xb stand for the recessive hemophilia allele.) X BX B X bX b X BX b

X bX b

Choose from the following list the three genotypes the parents must have in order for a daughter to have XbXb ? XY X BY B X bY b X bX b X bY X BX b X BX B

X bX b X bY X BX b

Mark the genotypes which express hemophilia. X bY XX b XY b X bX b YY b

XX b XY b

Why didn't Charles and Alexander, the grandsons of Queen Victoria, inherit hemophilia? because the disease is not carried on the "Y" chromosome because the disease is not on the "Y" chromosome and Helena does not have the trait because Helena carries the trait but it is not homozygous because Helena does not carry the trait

because the disease is not on the "Y" chromosome and Helena does not have the trait

Why would it be wise for a woman carrying the hemophilia gene to keep her son from being circumcised? because the probability of hemophilia would be 50% because the probability of hemophilia would be 25% because the probability of hemophilia would be 100%

because the probability of hemophilia would be 50%

Why didn't the two sons of Queen Victoria (Alfred and Arthur) display hemophilia? (refer to pedigree chart) because they received the dominant gene "Y" from their father because they are only carrying one recessive gene (b) because their father did not have the trait because they did not receive the recessive gene (X b) from their mother.

because they did not receive the recessive gene (X b) from their mother.

(Select all that apply.) Choose from the following list of diseases those that are sex-linked. night blindness rolling eyeballs nonfunctional sweat glands Huntington's disease white forelock muscular dystrophy certain deafness color blindness sickle-cell anemia diabetes

night blindness rolling eyeballs nonfunctional sweat glands white forelock muscular dystrophy certain deafness color blindness diabetes

The Rh ___________condition occurs in most of the world population.

positive

The condition of the Rh factor is called ____________when present and __________ when absent.

positive negative

The traits for blood type and Rh are the result of the presence or absence of particular _______ on the erythrocytes.

proteins

Sex-linked inheritance refers to _____________hereditary alleles usually being passed on the _chromosome.

recessive X

codominance

the condition in heterozygotes where both members of an allelic pair are present and contribute to the phenotype equally

The Talmud permitted a father with hemophilia to have his son circumcised. Would this preclude all possible problems? yes-because the father cannot pass on the trait yes-if the mother is not a possible carrier yes-if the mother was not X b X b (homozygous)

yes-if the mother is not a possible carrier