Genetics: HW 5, 6, & 7- Exam 2

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All DNA polymerases synthesize new DNA by adding nucleotides to the _____ of the growing DNA chain.

3' OH

What effect does crossing over have on linkage?

Crossing over generates recombination and leads to incomplete linkage

What does interference tell us about crossovers?

Interference tells us if one crossover inhibits a second crossover event.

Variations in chromosome number can be classified into which two basic types?

aneuploidy and polyploidy

Linked genes assort independently during meiosis

false

Mapping experiments become more accurate as the distance between genes increases

false

Which of the following is a common result of chromosomal duplication?

increased gene dosage

Compared to a two-point testcross, a three-point testcross:

is more accurate

Which of the following RNA molecules are required for the process of translation?

tRNA

Okazaki fragments are found in all of the following except

the leading strand

When in an electrical field, which direction will DNA travel?

towards the positive electrode

Linked genes always exhibit recombination frequencies of less than 50%

true

A species has a diploid chromosome number of 12. How many chromosomes will be found per cell in a double monosomic mutant and a tetrasomic mutant, respectively?

10,14

How many hydrogen bonds connect A and T bases?

2

If a DNA molecule is 30% C, what is the percentage of A?

20%

If a DNA molecule is 30% C, what is the percentage of G?

30%

An individual has the genotype Ab/aB. Gene loci A and B are 12 cM apart. If this individual is testcrossed, what percentage of the progeny will have the phenotype Ab?

44

An individual has the genotype Ab/aB. Gene loci A and B are 12 cM apart. If this individual is testcrossed, what percentage of the progeny will have the phenotype aB?

44

An individual has the genotype Ab/aB. Gene loci A and B are 12 cM apart. If this individual is testcrossed, what percentage of the progeny will have the phenotype AB?

6

An individual has the genotype Ab/aB. Gene loci A and B are 12 cM apart. If this individual is testcrossed, what percentage of the progeny will have the phenotype ab?

6

An individual has the genotype AB/ab. Gene loci A and B are 12 cM apart. If this individual is testcrossed, which progeny phenotypes are parental types?

AB and ab

An individual has the genotype AB/ab. Gene loci A and B are 12 cM apart. If this individual is testcrossed, which progeny phenotypes are recombinant types?

Ab and aB

Considering the structure of double-stranded DNA, what kinds of bonds hold the two complementary strands to each other?

hydrogen

Which of the following is a type of RNA that gets translated into a polypeptide.

mRNA

In the case of three linked loci, double crossovers always result in switching of the ____ loci

middle

The type of aneuploidy represented by 2n-2 is called

nullisomy

The arrangement in which each chromosome contains one wild type and one mutant allele is called _______ or ________.

repulsion; trans-configuration

Meselson and Stahl showed that DNA is replicated by a ______ system.

semiconservative


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