Muscle Tissue/ muscle cell/sacromere (UNIT 4)

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Troponin

Attached to tropomyosin, binds Ca2+ (muscle contraction)

Skeletal

Attaches to bone, voluntary, striated, multinucleated

Titin

'Tightens'/ connects to z lines(thin filament) on each end of sarcomere SPANS MYOSIN

m line

'middle', connect thick to thick filament

Contractile/myofilaments

'strands' directly involved in contraction

A bands

Everywhere there is thick filament/myosin

Cardiac

HEART, involuntary, striated, intercalated discs(gap junctions)

sarcoplasmic reticulum

High in Ca2+; covers myofibril

Nebulin

Holds actin strand together, makes up length of actin but actin will stay the same length SPANS ACTIN

Smooth

Lining of blood vessels/digestive tract/ respiratory tract, bladder, unstriated, single nuclei, tapered at ends, PASSAGEWAY TO MANY SYSTEMS

Myosin

Thick filaments, site for hydrolysis and actin binding site MOTOR

Actin

Thin filaments, subunits of g - actin, active sites for myosin binding

Structural protein

anchor and regulate length of myofilaments, alignment for optimal contraction

Myofibrils

contain sarcomeres

Tropomyosin

covers the active sites on g - actin molecules (blocks myosin binding sites, prevents cross-bridge formation)

Sarcoplasm

cytoplasm of a muscle fiber Contains: glycogen(sugar), myoglobin(stored oxygen)

z discs

end of sacromere, zig zags

Regulatory protein

found on actin

Multinucleated

more than one nucleus per cell

Zone of overlap

overlapping of myosin and actin

Transverse (T) tubules/triad

small tubes run across muscle fiber and allow things on sarcolemma to enter *Are located at zone of overlap

Sarcomeres

smalllest unit of contraction, formed by regulatory, contractile, and structural proteins

Endomysium

surrounds each fasicle

Epimysium

surrounds entire muscle

Perimysium

surrounds fascicles

Sarcolemma

surrounds outside of entire muscle fiber

h zone

thick filament/myosin ONLY

I bands

thin filament/actin ONLY

Dystrophin

transfers force of myofilament movement to sarcolemma and extracellular connective tissues

Terminal cisternae

Store Ca2+ and release when there is an AP


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