OM E6 - Oral Complications of H&N Cancer Treatment

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It appears while chemo can lead to viral/bacterial/fungal infections, radiation therapy can only lead to fungal infections.

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ACUTE Complications of Radiation Therapy

Mucositis Hypogeusia/dysgeusia Xerostomia Fungal infections

Complications of chemotherapy

Mucositis, oral ulceration Anemia, thrombocytopenia, leukopenia Infection: viral, bacterial, fungal Neurotoxicity: secondary to medication Osteonecrosis of the jaw: secondary to osteolytic medications Xerostomia

It has been brought up multiple times but which oral manifestation is a common complication of radiation therapy.

Oral Mucositis

LATE Complications of Radiation Therapy

Osteoradionecrosis Dental caries Trismus Increased loss of periodontal attachment Nutritional deficiencies Fungal infections Chronic pain

Trismus

Result of contraction of the masticatory muscles and TMJ capsules Usually occurs 3-6 months after radiation therapy Prevalence of 5-45% Maximum opening can be reduced to 5-15 mm

Orofacial pain treatment options

Topical anesthetic Analgesic Anti-inflammatory Antimicrobial Anticonvulsant Anxiolytic Antidepressant Muscle Relaxant

Fluoride therapy

Trays: 0.4% stannous fluoride gel; 1.0-1.1% NaF gel to be used for 10 minutes nightly Brush with fluoride toothpaste: Prevident 5000 plus

MRONJ

medication related osteonecrosis of the jaw

Osteoradionecrosis

the destruction and death of bone tissue from radiation therapy


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