Pharm Ch 40

A nurse is teaching a client about omeprazole, which has been prescribed as part of a regimen to treat an H. pylori infection. What statement, made by the client, suggests that the client understands proper use of the drug?

"I need to swallow the drug whole."

Antacids are contraindicated in pts with :

-abdominal pain -during lactation

GI stimulants functions

-facilitate emptying of the stomach contents into the small intestine

drugs that reduce production of HCl

-histamine H2 antagonists -proton pump inhibitors

H. plyori

-infection in pts with active duodenal ulcers -treated by proton pump inhibitors

other oral drugs should not be administered within ______ hours of an antacid

1-2 hours

The nurse is caring for a client who is receiving antacids to relieve GI discomfort. What nursing action is most appropriate?

Administer the antacid 1 hour before or 2 hours after other oral medications.

A common drug regimen for eradication of H. pylori includes a proton pump inhibitor (PPI) and two antibiotics. What is one of the preferred antibiotics?

Amoxicillin

An older adult has been taking a calcium-based antacid on an increasingly frequent basis. When teaching this client, the nurse should include suggestions for the prevention of which adverse effect?

Constipation

A client has been prescribed rabeprazole (Aciphex). It will be important for the nurse to assess the client's drug history to determine if the client is taking which drug?

Digoxin

Administering an antacid to a client taking which medications will decrease the absorption of the medication and result in a decreased drug effect?

Digoxin

A client arrives at the walk-in clinic reporting vomiting and a burning sensation in the mid-epigastric region. The nurse suspects that the client has peptic ulcer disease. Which is a potential cause of peptic ulcer disease?

Infection with H. pylori

A client is taking nonsteroidal anti-inflammatory agents for arthritis of the knees and hips. Which disease is a result of cellular destruction of the gastrointestinal tract from this medication?

Peptic ulcer disease

The nurse administers ranitidine cautiously to clients with evidence of what condition?

Renal disease

The following data identified during a nursing assessment and interview. When considering risks for the development of a peptic ulcer, which situation should the nurse discuss with the client?

Self medicates with a nonsteroidal anti-inflammatory drug (NSAID) daily

gastric stasis

failure of the body to remove stomach contents normally

gastric stasis

failure to move food normally out of the stomach

A nurse is providing education to an adult female client who has been prescribed misoprostol. What instruction should the nurse include in the teaching?

Use effective contraceptive measures

drugs that neutralize HCl and protect mucosal lining

antacids

Misoprostol is a synthetic form of prostaglandin E prescribed to protect the gastric mucosa from erosion and ulceration. The drug is contraindicated in clients who:

are pregnant

emetogenic

causing vomiting

hypersecretory

characterized by excessive secretion of a substance

Antacids are alkaline substances primarily used to directly neutralize gastric acid in the stomach to prevent/treat PUD, GERD, heartburn, and GI bleed. In the treatment of what medical diagnosis might aluminum-based antacids be used?

chronic renal failure hyperphosphatemia

Magnesium containing antacids are contraindicated in pts with :

decreased kidney function

chemoreceptor trigger zone (CTZ)

group of nerve fibers located on the surface of the fourth ventricle of the brain that, when stimulated, results in vomiting

The client will receive ranitidine (Zantac) 150 mg PO at bedtime. Prior to administration, the nurse should inform the client that common side effects related to this medication include:

headache

upper GI system consists of :

mouth, esophagus, and stomach

acid reduction increases/reduces absorption of food and drugs in stomach

reduces

gastroesophageal reflux disease (GERD)

reflux or backup of gastric contents into the esophagus

A client, with recent abdominal pain and a 40-pack per year smoking history, is prescribed a treatment regimen for a diagnosis of duodenal ulcer. What important teaching would the nurse include in relation to treatment?

smoking effects on the healing of ulcers

vomiting

spasmodic ejection of stomach contents through the mouth

What is an effect of histamine release that is related to ulcer formation?

stimulates gastric acid secretion

hydrochloric acid (HCl)

stomach acid that aids in digestion

Helicobacter pylori define

stomach bacterium that causes peptic ulcer; also known as H. pylori (define)

nausea

unpleasant and uncomfortable feeling in the stomach, sometimes followed by vomiting

vertigo

feeling of a spinning or rotational motion; dizziness

Calcium containing antacids are contraindicated in pts with :

-renal impairment -hypercalcemia -respiratory insufficiency -cardiac disease