RAT 1

Nucleosomes consist of a _______ -long strecth of _________ associated to ________ of each of the _______________

200 bp; DNA; two copies; core histones

Further coiling of the basic beads-on-a-string chromatin fiber generates a thicker fiber whose thickness is about

30 nm

"In Schizosaccharomyces pombe, functional centromeres have been shown to consist of a sequence spanning about 125 bp"

False

Centromeres are only present during mitosis

False

The level of condensation of a gene is not an important factor dictating whether the gene will be expressed or not

False

The total extended length of all human chromosomes put one next to the other is about

Two Meters

"In humans, a defining characteristic of centromeric regions is the presence of"

a variant form of histone H3 known as CENP-A

The main function of the centromere is to

allow the proper distribution of chromosomes to daughter cells during mitosis

"Telomeres are sequences located __________, and they are characterized by containing __________________ that _________________________"

at the ends of chromosomes; numerous repeats of a simple DNA sequence; form a looped structure