SUB ABU 4
A drug is ___________ when it changes from solid to liquid after being mixed with a liquid. a. dissolved b. suspended c. diffused d. absorbed
a.
Drinking large quantities of water would be an example of an attempt to alter the results of a drug test by _________. a. dilution b. adulteration c. substitution d. diffusion
a.
How long can alcohol be detected in the system by using a drug test? a. up to one day b. up to one week c. up to one month d. None of these are correct.
a.
One way that ____________ is administered involves sprinkling it on marijuana and smoking it. a. PCP b. MDA c. LSD d. psilocybin
a.
When drugs are swallowed, they pass through the stomach and are absorbed in the __________. a. small intestine b. kidneys c. liver d. large intestine
a.
Which of the following conditions lead to more rapid drug absorption? a. when there is more blood flow at the site of absorption b. when the absorbing surface is smaller c. when drugs are taken in suspension, rather than aqueous solution d. All of these are correct.
a.
Which of the following results has not been demonstrated in needle exchange programs? a. an increase in IV drug use b. less needle sharing c. improved needle cleaning practices d. All of these have resulted from needle exchange programs.
a.
Which of the following systems does not receive major portions of a drug rapidly due to a high volume of drug flow? a. muscles b. heart c. brain d. kidney
a.
_____ is a term that refers to the diminished effect of a drug when another drug is present. a. Antagonism b. Synergism c. Potentiation d. Rebound
a.
__________ reflects the amount of latitude there is in a drug dose before a stronger effect is reached. a. Slope b. Potency c. Effective dose d. Synergism
a.
___________ is the portion of the original drug dose that reaches its site of action or that reaches a fluid in the body that gives the drug access to its site of action. a. Bioavailability b. Effective dose c. Therapeutic index d. Drug potency
a.
____________ means that the rate at which a drug is metabolized is independent of its concentration in the blood. a. Zero-order kinetics b. First-order kinetics c. First-pass metabolization d. Bioavailability
a.
A drug that is administered transdermally _______________. a. is placed under the tongue b. passes through the skin c. is injected into muscle tissue d. is sniffed
b.
A person who wants to experience the effects of a drug immediately should administer it how? a. transdermally b. intravenously c. nasally d. sublingually
b.
In __________, the combined effects of multiple drugs is greater than the sum of the parts. a. summation b. potentiation c. exponentiation d. antagonism
b.
Once in the bloodstream, orally administered drugs pass through the __________ before reaching the brain. a. kidneys b. liver c. pancreas d. pituitary gland
b.
People get drunk faster when drinking alcohol on an empty stomach than after they have eaten some food. This difference in response a. distribution b. absorption c. diffusion d. elimination
b.
The __________ is the most important organ for excretion of drugs and their metabolites. a. liver b. kidney c. pancreas d. bowel
b.
The effect of a drug depends most fundamentally on __________. a. body size b. dosage c. psychological set d. lipid profile
b.
The elimination of a drug from the body often is associated with changes that are opposite to those that were caused by the drug. These are sometimes called __________. a. flashbacks b. rebound effects c. delirium tremens d. withdrawal symptoms
b.
The fact that oil and water are not easily mixed is an example of which concept? a. assimilation b. solubility c. elimination d. diffusibility
b.
The process by which the body breaks down matter into more simple components and waste is known as ____________. a. absorption b. metabolism c. synthesis d. biotransformation
b.
When, in a series of events, what happens in a later event alters those preceding it, it is known as a _____________ relationship. a. contingent b. feedback c. causal d. concurrent
b.
Which of the following is not an advantage of the oral route of drug administration? a. It is safe. b. It causes fast absorption. c. It is convenient. d. It is economical
b.
Which of the following is the easiest drug injection route to use? a. intramuscular b. subcutaneous c. oral d. intravenous
b.
____________ is an example of a medication that is administered sublingually. a. Lithium b. Nitroglycerin c. Insulin d. Prozac
b.
A chronic user of amphetamines would likely ________ their drug of choice. a. snort b. smoke c. inject d. swallow
c.
A common street term for injecting a drug intravenously is __________. a. freebasing b. chuffing c. mainlining d. tripping
c.
Discussions related to drug elimination often refer to a unit of measurement known as ________. a. come-down cycle b. metabo-time c. half-life d. zero-hour
c.
Due to differences in ________, proper drug dosage is determined by an individual's weight. a. body fat b. bone mass c. body fluid d. blood volume
c.
In research, _________ means to be able to account for variables that may affect the results of a study. a. independence b. blindness c. control d. none of these
c.
People who wear a nicotine patch to help them quit smoking receive a dose of the drug through which route of administration? a. sublingually b. intranasally c. transdermally d. subcutaneously
c.
The benefits of administering a drug orally must be weighed against the drawbacks relating to ________. a. infection b. elimination c. time d. expense
c.
The therapeutic index is _____. a. a list of the effective doses of medications b. the dosage of a drug needed to produce its intended effect c. a measure of a drug's safety in medical care d. computed as the ratio ED 50/ LD 50
c.
What does the pharmacological phrase ED 60 mean? a. 60% of nonhuman lab animals die at this particular dose b. 40% of nonhuman lab animals die at this particular dose c. 60% of the patients who receive a given dose will experience a particular effect d. 40% of the patients who receive a given dose will experience a particular effect
c.
Which of the following best reflects subcutaneous injection and absorption rate? a. slow and sporadic b. rapid and sporadic c. slow and constant d. rapid and constant
c.
Which of the following drugs can be detected in the system for up to one month following chronic use? a. opiates b. benzodiazepines c. marijuana d. cocaine
c.
Which of the following is an example of an inhalant? a. nitroglycerin b. cocaine c. benzene d. snuff
c.
Which of the following is most rapidly absorbed? a. drugs taken in solid form b. drugs taken in suspension c. drugs taken in water solution d. drugs taken in oily solution
c.
___ is the study of the biochemical and physiological effects of drugs and their mechanisms of action. a. Pharmacokinetics b. Psychopharmacology c. Pharmacodynamics d. Biochemistry
c.
__________ is a term referring to the minimum dose of a drug that yields its efficacy. a. Effective dose b. Therapeutic index c. Drug potency d. Placebo
c.
A drug that is taken sublingually is __________. a. injected just below the skin surface b. sniffed c. dropped into the eye d. placed under the tongue
d.
A drug's dose is calculated according to a person's __________. a. age b. sex c. tolerance d. weight
d.
Enzymes in the __________ are important in the metabolization of drugs. a. kidneys b. liver c. gastrointestinal tract d. All of these are correct.
d.
In a prototypic dose-effect curve, the vertical axis refers to the __________ and the horizontal axis refers to the __________. a. range of drug doses, effect size b. effect size, number of drugs c. number of drugs, effect size d. effect size, range of drug doses
d.
The presence of food in the stomach __________ absorption and __________ the maximum drug level achieved for orally administered drugs. a. speeds up; increases b. speeds up; decreases c. delays; increases d. delays; decreases
d.
Which of the following affect drug distribution? a. blood flow b. fat solubility of the drug c. diffusibility of membranes d. All of these are correct.
d.
Which of the following drug states is not suitable for administration via inhalation? a. suspension b. gas c. liquid d. powder
d.
Which of the following drugs is commonly snorted? a. cocaine b. heroin c. tobacco d. All of these are correct.
d.
Which of the following is a common site for intramuscular drug injection? a. buttocks b. deltoid c. thigh d. All of these are correct.
d.
Which route of drug administration is considered the best overall? a. intramuscular b. sublingual c. oral d. none
d.
Which of the following is a method used to administer barbiturates? a. oral b. rectal c. subcutaneous d. intramuscular e. All of these are correct.
e.
Which of the following is not a way in which drugs are excreted from the body? a. directly in the feces b. in liver bile c. in mother's milk d. through the lungs e. All of these are ways in which drugs are excreted.
e.
