types of genetic changes

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horizontal gene transfer

a copy of a bacterial gene is now found integrated in the genome of another species of bacteria

exon shuffling

protein becomes much more unstable

mutation within a gene

protein becomes much more unstable

gene duplication and divergence

tandem copies of a gene are found in the genome

exon shuffling

a protein acquires a DNA-binding domain

mutation in regulatory DNA

a protein normally expressed only in the liver is now expressed in blood cells

exon shuffling

a protein normally normalized in the nuclei is now localized in the cytoplasm

mutation within a gene

a protein normally normalized in the nuclei is now localized in the cytoplasm


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