Week 7 Check Your Understanding Assignment PATHO: 370

In the United States, nearly ________ people have diabetes mellitus.

29.1 million

What effect would adrenocortical insufficiency have on an individual's response to surgical stress?

More prone to hypotension

Which response to an injection of ACTH indicates a primary adrenal insufficiency?

No change in serum glucocorticoid level

________ is the most powerful predictor of developing type 2 diabetes mellitus.

Obesity

________ disease is a rare autosomal recessive disorder in which excessive amounts of copper accumulate in the liver.

Wilson

An early indicator of colon cancer is

a change in bowel habits.

More than half of the initial cases of pancreatitis are associated with

alcoholism.

Aldosterone secretion is regulated by the presence of ________ in the circulation.

angiotensin II

Acute right lower quadrant pain associated with rebound tenderness and systemic signs of inflammation are indicative of

appendicitis.

It is true that Graves disease is

associated with autoantibodies to TSH receptors.

Hepatitis with the presence of autoantibodies and positive antinuclear antibodies (ANA) is

autoimmune hepatitis.

A patient who should be routinely evaluated for peptic ulcer disease is one who is

being treated with high-dose oral glucocorticoids.

Congenital adrenal hyperplasia (adrenogenital syndrome) results from

blocked cortisol production.

Hepatitis B is usually transmitted by exposure to

blood or semen.

Ulcerative colitis is commonly associated with

bloody diarrhea.

Most gallstones are composed of

cholesterol.

Proton pump inhibitors may be used in the management of peptic ulcer disease to

decrease hydrochloric acid (HCl) secretion.

Diabetic neuropathy is thought to result from

decreased myoinositol transport.

An increase in ADH secretion occurs in response to

dehydration.

A patient with a history of alcoholism presents with hematemesis and profound anemia. The expected diagnosis is

gastroesophageal varices.

The most common causes of prehepatic jaundice are ________ and ineffective erythropoiesis.

hemolysis

An increased urine bilirubin is associated with

hepatitis.

The signs and symptoms of adrenocortical hormone excess may occur from either a primary or secondary disorder. A symptom associated with primary Cushing syndrome is

hyperglycemia.

A patient with pancreatitis may experience muscle cramps secondary to

hypocalcemia.

A laboratory finding that would help confirm the diagnosis of hyperaldosteronism is

hypokalemia.

A clinical finding consistent with a diagnosis of syndrome of inappropriate ADH secretion (SIADH) is

hyponatremia.

A patient presenting with muscle cramps, fatigue, anxiety, depression, and prolonged Q-T intervals on EKG may be showing symptoms of

hypoparathyroidism.

Surgical removal of a gland may result in

hyposecretion.

The formation of active vitamin D

is impaired in renal failure.

It is true that the synthesis of thyroid hormones

is inhibited by iodine deficiency.

Brain injury secondary to high serum bilirubin is called

kernicterus.

The American Diabetes Association recommends a postprandial blood glucose level of ________ mg/dL for adults with diabetes.

less than 180

Rupture of esophageal varices is a complication of cirrhosis with portal hypertension and carries a high ________ rate.

mortality

Premature infants are at greater risk for developing

necrotizing enterocolitis.

The underlying pathogenic mechanism for type 1 diabetes is

pancreatic β-cell destruction.

Barrett esophagus is a

preneoplastic lesion.

In type I diabetes, respiratory compensation may occur through a process of

respiratory alkalosis.

Clinical manifestations of hypoparathyroidism

result from decreased serum ionized calcium.

It is true that growth hormone excess in adults

results in the condition of acromegaly.

Diabetes mellitus is the ________ leading cause of death and a major cause of disability in the United States.

seventh

Narcotic administration should be administered carefully in patients with acute pancreatitis related to potential for

sphincter of Oddi dysfunction.

A patient receiving chemotherapy may be at greater risk for development of

stomatitis.

It is true that biliary cancer

tend to be asymptomatic and progress insidiously.

Clinical manifestations of Graves disease may include

tremor.

A clinical finding consistent with a hypoglycemic reaction is

tremors.

Antidiuretic hormone (ADH) increases

water reabsorption in the collecting tubule of the kidney.

Normal bile is composed of

water, electrolytes, and organic solutes.

What form of viral hepatitis is likely to be transmitted sexually?

Hepatitis B

A biliary cause of acute pancreatitis is suggested by an elevation in which serum laboratory results?

Alkaline phosphatase

A patient reporting vision changes, photophobia, and lid lag may be exhibiting signs of

Graves disease.

Which symptom suggests the presence of a hiatal hernia?

Heartburn

What finding should prompt further diagnostic testing in a child presenting with diarrhea?

Blood and mucus in the stools

What finding would rule out a diagnosis of irritable bowel syndrome in a patient with chronic diarrhea?

Bloody stools

What clinical finding would suggest an esophageal cause of a client's report of dysphagia?

Chest pain during meals

What laboratory data would support a diagnosis of hemochromatosis?

Elevated ferritin

What indicator is most helpful in evaluating long-term blood glucose management in patients with diabetes mellitus?

Glycosylated hemoglobin levels (HbA1c)

A patient with chronic gastritis would likely be tested for

Helicobacter pylori.

An urgent surgical consult is indicated for the patient with acute abdominal pain and

absent bowel sounds.

A viral hepatitis screen with positive hepatitis B surface antigen (HBsAg) should be interpreted as ________ hepatitis B.

acute

The most common cause of mechanical bowel obstruction is

adhesions.

Liver transaminase elevations in which aspartate aminotransferase (AST) is markedly greater than alanine aminotransferase (ALT) is characteristic of

alcohol-induced injury.

An infusion of mannitol would be prescribed to treat

cerebral edema.

The definitive treatment for cholecystitis is

cholecystectomy.

Chronic pancreatitis may lead to

diabetes mellitus.

Fecal leukocyte screening would be indicated in a patient with suspected

enterocolitis.

Steatohepatitis is caused by an accumulation of ________ in the liver cells.

fat

A silent abdomen 3 hours after bowel surgery most likely indicates

functional bowel obstruction.

Untreated acute cholecystitis may lead to ________ of the gallbladder wall.

gangrene

Dumping syndrome is commonly seen after __________ procedures.

gastric bypass

Epigastric pain that is relieved by food is suggestive of

gastric ulcer.

The breakdown of stored glycogen in the liver and muscles is called

glycogenolysis.

A thyroid gland that grows larger than normal is known as

goiter.

A clinical finding that is consistent with a diagnosis of adrenocortical insufficiency is

hypoglycemia.

Myxedema coma is a severe condition associated with

hypothyroidism.

Hepatic encephalopathy is associated with

increased blood ammonia levels.

Insulin binding to its receptor on target cells results in

increased facilitated cellular diffusion of glucose.

Constipation in an elderly patient can be best treated by

increasing fiber in the diet.

The finding of hypotension, rigid abdomen, and absent bowel sounds in a patient with pancreatitis

indicates peritonitis with substantial risk for sepsis and shock.

Celiac sprue is a malabsorptive disorder associated with

inflammatory reaction to gluten-containing foods.

Propylthiouracil may be used to treat hyperthyroidism, because it

inhibits thyroid hormone synthesis.

The underlying pathogenic mechanism for type 2 diabetes is

insulin resistance and β-cell dysfunction.

Jaundice is a common manifestation of

liver disease.

A patient being treated for hepatic encephalopathy could be expected to receive a(n) ________ diet.

low-protein and high-fiber

It is true that gallstones are

more common in women.

Radioactive iodine treatment is the therapy of choice in patients with Graves disease. The patient should be expected to

need lifelong thyroid replacement therapy.

Type 2 diabetes mellitus is often associated with

nonketotic hyperosmolality.

Growth hormone-deficient infants would display

normal birth length and weight.

A patient admitted with bleeding related to esophageal varices could be expected to receive a continuous intravenous infusion of

octreotide acetate.

Calcitonin is produced by thyroid parafollicular cells and increases bone formation by

osteoblasts.

The most challenging aspect of treatment for chronic pancreatitis is

pain control.

A tumor which results in excessive production and release of catecholamines is

pheochromocytoma.

Esophageal varices represent a complication of ________ hypertension.

portal

Pathophysiologically, esophageal varices can be attributed to

portal hypertension.

A type of insulin that would be most appropriate for acute management of hyperglycemia is

regular.

Patients with acute pancreatitis are generally made NPO and may require continuous gastric suctioning in order to

remove the usual stimuli for pancreatic secretion.

Diabetes insipidus is a condition that

results from inadequate ADH secretion.

The pain associated with chronic pancreatitis is generally described as ________ in nature.

steady and boring