Women's Health and Maternity/Newborn Drugs Level 1

Which antihypertensive drug is contraindicated in lactating women? a. Atenolol b. Labetalol c. Metoprolol d. Propranolol

a. Atenolol rational: Atenolol is contraindicated in lactating woman because it enters the breast milk and may cause adverse effects to the neonate. Labetalol and propranolol are safe to administer during lactation. Metoprolol is a safe drug to be taken during pregnancy.

Which oxytocic drug may help to control uterine bleeding post-delivery and promote milk ejection? a. Oxytocin b. Mifepristone c. Dinoprostone d. Ergot alkaloids

a. Oxytocin Oxytocin is used to induce labor, control uterine bleeding after delivery, and promote milk ejection during lactation. Mifepristone is generally used to induce abortion. Dinoprostone induces labor but has no effect on milk ejection or uterine bleeding. Although ergot alkaloids control uterine bleeding after delivery, they do not cause milk ejection during lactation.

A registered nurse teaches a nursing student about the effects of aspirin in pregnant women. Which statement made by the nursing student indicates a need for further teaching? a. "Aspirin may reduce a fever." b. "Aspirin may cause Reye syndrome." c. "Aspirin may increase the risk of bleeding." d. "Aspirin may suppress labor contractions."

b. "Aspirin may cause Reye syndrome." Aspirin does not cause Reye syndrome in pregnant clients. Aspirin may reduce fever, increase the risk of bleeding, and suppress labor contractions.

The clinic nurse is planning care for a client found to have chlamydia. Which treatment should the nurse plan to implement? a. Administration of 250 mg of acyclovir orally in a single dose b. Administration of 1 g of azithromycin orally in a single dose c. Administration of 250 mg of ceftriaxone intramuscularly in a single dose d. Administration of 2.4 million units of benzathine penicillin G intramuscularly in a single dose

b. Administration of 1 g of azithromycin orally in a single dose The treatment of choice for chlamydial infection is 1 g of azithromycin orally in a single dose. The one-dose course is preferred because of its ease of completion. Acyclovir may be prescribed in a 7-day course for a genital herpes outbreak. Administering 250 mg of ceftriaxone intramuscularly in a single dose is the drug therapy recommended for gonorrhea. Benzathine penicillin G given intramuscularly as a single 2.4 million unit dose is the treatment for primary, secondary, and early latent syphilis.

Which medication is indicated for evacuation in case of a miscarriage? a. Clomiphene b. Dinoprostone c. Magnesium sulfate d. Methylergonovine

b. Dinoprostone rational: Dinoprostone is a prostaglandin E2 abortifacient and cervical ripening drug, which is indicated for uterine evacuation in cases of miscarriage. Clomiphene is indicated for female infertility in some clients. Magnesium sulfate is used to treat pregnancy-induced hypertension. Methylergonovine is used to treat postpartum uterine atony and hemorrhage.

Which drug may cause malformations of the male external genitalia? a. Etretinate b. Dutasteride c.Methimazole d.Propylthiouracil

b. Dutasteride rational: Dutasteride is a 5-alpha-reductase inhibitor that causes malformations of external genitalia in males. Etretinate is a vitamin A derivative that may cause multiple central nervous system defects. Methimazole and propylthiouracil are antithyroid drugs that may cause goiters and hypothyroidism.

breastfeeding mother requires treatment for depression. Which drug would be safe to use if the mother wishes to continue breastfeeding the newborn? a. Fluoxetine b. Paroxetine c. Valproic acid d. Methotrexate

b. Paroxetine Paroxetine can be safely given during breastfeeding. Fluoxetine can easily enter breast milk; therefore this drug would only be used when other selective serotonin reuptake inhibitors are ineffective. Valproic acid is an antiepileptic drug that can be given safely to breastfeeding women. Methotrexate is an anticancer drug that cannot be given during breastfeeding because it enters the breast milk and can cause adverse effects in the baby.

Which drug is used to manage nonmetastatic gestational trophoblastic disease? a. Oxytocin b. Mifepristone c. Dinoprostone d. Methylergonovine

c. Dinoprostone Dinoprostone is a synthetic drug derived from naturally occurring prostaglandins. This drug is used to manage nonmetastatic gestational trophoblastic disease. Methylergonovine is used to treat postpartum hemorrhage. Oxytocin is used for labor induction. Mifepristone is used to induce an abortion.

Which situation is an indication for an oxytocin infusion? a. Hypertonic uterus b. Pelvic inflammatory disease c. Induction of labor at full-term d. Cervical stenosis in a client who is in labor

c. Induction of labor at full-term Oxytocin induces labor at full-term gestation, which stimulates uterine contractions and helps the woman to have an easy delivery. Oxytocin is contraindicated in hypertonic uterus, pelvic inflammatory disease, and cervical stenosis.

Which ovulation stimulant is derived from the urine of postmenopausal women? a. Oxytocin b. Clomiphene c. Menotropins d. Dinoprostone

c. Menotropins Menotropins are a standardized mixture of follicle-stimulating hormones and luteinizing hormones. These chemicals are derived from the urine of postmenopausal women. Clomiphene is a synthetic ovulation stimulant. Oxytocin and dinoprostone are synthetic uterine stimulants.

What complication should a nurse be alert for in a client receiving an oxytocin infusion to induce labor? a. Intense pain b. Uterine tetany c. Hypoglycemia d. Umbilical cord prolapse

b. Uterine tetany rational: Because oxytocin promotes powerful uterine contractions, uterine tetany may occur. The oxytocin infusion must be stopped to prevent uterine rupture and fetal compromise. Intense pain can be associated with strong uterine contractions; this is not a complication. Hypoglycemia is unrelated to uterine contractions. Umbilical cord prolapse is not likely to occur when induction of labor is initiated.