2 blood types, blood transfusion and tissue and organ transplantation

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take one part of an organism and place it on another location on the same organism

autograft

transplant between identical twins

isograft

univeral donor

o

transplant between same species

allograft

relative frequency of blood types % O A B AB

47 41 9 3

three different gene variants, which are dominant

A B O A and B are dominant

two types of antigens that stimulate blood transfusion rxns

OAB system and Rh system

if A + blood is transfused into a A - person what happens

Rh negative, this person can develop antibodies slowly in 2-4 months

__ is important during pregnancy and to prevent transfusion reactions

Rh typing

on the surface of red blood cells causes most blood transfusion reactions

a b antigens

universal recipient

ab+

antibodies in the plasma and are usually igG and igM

agglutinins

blood typing happens when you separate rbc and they are diluted with saline, treated with agglutinin sadsjfgnfdgj

agkdfgj

occurs when blood is transfused from one person to another with person who has a diff blood type it results in agglutination and hemolysis of rbc

blood transfusion reaction

A B O

blood types

used to identify donor blood so that matching the recipient can decrease the likelihood of transfusion reactions

blood typing

disease of fetus and newborn

erythroblastosis fetalis

there are six hla antigens that commonly cause

graft rejection

how can we prevent graft rejection

tissue typing (match of 6 hla proteins, very difficult)

the presence or absence of agglutinogens influence blood

type

transplant between different species

xenograft


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