402 Exam 3.0 - pharm
what should the nurse monitor for a pt taking hydroxyurea
ALT/AST Q2weeks
most life-threatening SE of filgastrim
ARDS
SE of filgrastim (5)
ARDS thrombocytopnea alveolar humorrhage n/v bone pain
Which adverse effects will the nurse monitor for in a patient receiving chemotherapy? (Select all that apply) a. Alopecia b. Stomatitis c. Neutropenia d. Hypertension e. Urinary retention
a, b, c
The nurse should recognize that a high tissue growth fraction allows chemotherapeutic medications to be more toxic to tissues in which phases of the cell cycle? (Select all that apply) a. S b. G 1 c. G 0 d. M e. G 2
a, b, d, e
When administering anticancer drugs, the nurse should identify which interventions as effective in minimizing renal injury from hyperuricemia? a. Administration of fluids b. Administration of rasburicase [Elitek] c. Premedication with ondansetron [Zofran] d. Premedication with dexamethasone [Decadron] e. Prophylactic administration of allopurinol [Zyloprim]
a, b, e
A nurse is describing the characteristics of neoplastic cells to a patient. Which information will the nurse include in the teaching session? (select all that apply) a. Immortality b. Noninvasive growth c. Persistent proliferation d. Formation of metastases e. Progressively shorter telomeres
a, c, d
The nurse should review which baseline data before starting epoetin alfa [Epogen] therapy in a patient with chronic renal failure (CRF)? (Select all that apply) a. Ferritin level b. Blood glucose level c. Temperature trends d. Blood pressure trends e. Hemoglobin and hematocrit
a, d, e
The healthcare provider prescribes hematopoietic growth factor for a patient. The nurse should notify the healthcare provider to question the prescription for which patient condition? a. Uncontrolled hypertension b. Chronic renal failure (CRF) c. Nonmyeloid malignancy chemotherapy-induced anemia d. Human immunodeficiency virus (HIV), for which the patient is receiving zidovudine
a.
The nurse is caring for a patient undergoing chemotherapy for breast cancer. Which should the nurse recognize as the rationale for using more than one chemotherapy drug simultaneously? a. Drug resistance occurs less frequently. b. Normal cell repopulation is not necessary. c. The intervals between dosages are shorter. d. The effect occurs during the mitotic phase of the cell cycle
a.
The nurse is caring for a patient with anemia related to chronic renal failure. Which agent might be used to treat the anemia? a. epoetin alfa b. filgrastim c. oprelvekin d. sargramostim
a.
what should the nurse monitor for a pt taking filgastrim?
absoulte neutrophils
A patient with nonmyeloid cancer is receiving oprelvekin [Neumega]. Which symptom(s), if observed in this patient, would prompt the nurse to notify the provider of an adverse reaction to the oprelvekin [Neumega]? . (select all that aooly) a. Hypertension b. Fluid retention c. Atrial fibrillation d. Anaphylactic reactions e. Accelerated tumor progression
b, c, d
Which statements regarding treatment modalities for cancer should the nurse identify as true? (select all that apply) a. Irradiation is the treatment of choice for leukemias. b. Surgery is the most common treatment for solid cancers. c. Drug therapy is the treatment of choice for disseminated cancers. d. Drug therapy is not effective in treating a patient with cancer who has had surgery. e. Drug therapy is effective as an adjunct therapy in treating a patient who has had irradiation.
b, c, e
A maintenance dose of epoetin alfa [Epogen] is ordered for a patient undergoing dialysis for chronic renal failure. The nurse should anticipate administering which dosage of epoetin alfa [Epogen]? a. 40,000 units subQ weekly b. 75 units/kg IV 3 times/week c. 100 units/kg IV 3 times/week d. 150 units/kg subQ 3 times/week
b.
A patient is receiving cancer chemotherapy. Which type of drug is the nurse administering? a. Targeted drugs b. Cytotoxic agents c. Biologic response modifiers d. Hormones and hormone antagonist
b.
The nurse is evaluating the effectiveness of the drug oprelvekin [Neumega] in a patient undergoing cancer chemotherapy. Which finding is most indicative that this drug is having its intended effect? a. Hemoglobin level of 13.2 g/dL b. Platelet count of 150 × 103/mm 3 c. White blood cell count of 5500/mm 3 d. Total lymphocyte count of 1000/mm 3
b.
The nurse should identify which class of anticancer drugs as used most often in the treatment of patients? a. Targeted drugs b. Cytotoxic drugs c. Immunomodulating agents d. Biologic response modifiers
b.
Which cytotoxic anticancer drug should the nurse identify as being the least emetogenic agent? a. Cisplatin b. Bleomycin c. Carboplatin d. Methotrexate [Rheumatrex]
b.
Chemotherapy is dose limiting primarily because of toxicity to the cells in which tissues ? (select all that apply) a. liver b. brain c. bone marrow d. sperm forming cells e. GI lining
c, d, e
A cancer patient who is on chemotherapy reports severe nausea and vomiting. Which action would be most beneficial to the patient? a. Wash hands often. b. Administer allopurinol [Zyloprim]. c. Administer ondansetron [Zofran]. d. Wash lettuce before serving
c.
A nurse is teaching a health class about screening tests. Which information should the nurse include in the teaching session? a. Cervical cancer screening should begin after the age of 21. b. All men over the age of 50 should have a prostate-specific antigen test done yearly. c. Beginning at age 50, both men and women should have a flexible sigmoidoscopy every 5 years. d. Women ages 20-39 should have an annual mammogram and annual clinical breast examination
c.
A patient is on chemotherapy. Following periodic lab work, the nurse instructs the patient to use a soft-bristled toothbrush and to avoid activities that may increase risk of injury. What is the rationale for the nurse's instructions? a. The patient has developed anemia. b. The patient has developed neutropenia. c. The patient has developed thrombocytopenia. d. The patient has developed sores in the oral cavity
c.
A patient with cancer who is neutropenic is hospitalized. Which action by the nursing assistant requires the supervising nurse to intervene? a. Maintaining isolation protocol for the patient b. Assisting the patient in basic hygiene as needed c. Delivering a fresh fruit basket to the patient's room d. Obtaining the patient's temperature at frequent intervals
c.
A patient with liver cancer requires considerable assistance and frequent medical care. The nurse would give this patient which Karnofsky Performance Scale score? a. 90 b. 80 c. 50 d. 20
c.
The nurse develops a plan of care for a patient receiving chemotherapy whose neutrophil count has reached the nadir. Which nursing action is the priority? a. limit contact with visitors b. provide daily oral hgiene c. obtain temp frequently d. restrict all gresh fuits and beggies
c.
The nurse is explaining the use of romiplostim [Nplate] to treat idiopathic thrombocytopenic purpura (ITP). Which patient statement indicates understanding of the nurse's explanation? a. "I will have my white blood cell count evaluated in 1 month." b. "I'll call my healthcare provider if I notice any swelling in my legs." c. "I'll let my healthcare provider know if I have any pain in my joints." d. "I shouldn't take this medication with food because that prevents absorption of the drug."
c.
Which characteristic of cancer cells can be described as "unresponsiveness to feedback mechanisms that control cellular growth in healthy tissue?" a. Invasive growth b. Telomerase activity c. Persistent proliferation d. Formation of metastases
c.
Which finding indicates a positive outcome from treatment with filgrastim [Neupogen]? a. Bone pain is eliminated. b. The cancer goes into remission. c. The neutrophil count increases. d. The red blood cell count increases
c.
A cancer patient is receiving a combination of cancer drugs. How should the nurse interpret this finding? a. The patient is terminal. b. The patient has an infection. c. This activates P-glycoprotein. d. This prevents drug resistance
d.
A cancer patient wants to know what the word nadir means. What is the nurse's best response? a. "It is the patient's tolerance to the chemotherapy's bone marrow suppressant effect." b. "It is the time it takes the bone marrow to completely recover from a dose of chemotherapy." c. "It is the maximum dose for a chemotherapy drug in reference to bone marrow suppression effects." d. "It is the average number of days it takes for chemotherapy to decrease the neutrophil count to its lowest level."
d.
A patient is receiving filgrastim. Which assessment finding indicates that the medication has been effective? a. A decrease in platelets b. A decrease in stomatitis c. An increase in red blood cells d. An increase in white blood cells
d.
The nurse is administering epoetin alfa [Procrit] to a patient receiving chemotherapy. Which adverse effect is a potential risk with this drug? a. bone pain b. hypotension c. easy bruising d. accelerated tumor progession
d.
The nurse is caring for a patient who has mild thrombocytopenia after chemotherapy. Which action should the nurse take? a. Administer a colony-stimulating factor. b. Take the pulse before and after activity. c. Obtain blood cultures and then begin antibiotic therapy. d. Use minimal cuff inflation when taking the blood pressure.
d.
drug given to sickle cell patients that didn't respond to hydroxyurea
erythropoetin
use of allopurinol
gout
SE of vincristine (4)
hepatotoxicity seizures thrombocytopnea extravacation (leakage of fluids)
med given to sickle cell patients to increase HgF production and retard sickling
hydroxyurea
SE of interleukin 2
hypoxia
what are the main complains of patients taking hydroxyneuria
hypoxia pain dehydration
action of filgrastim
increases neutophil count
what should the nurse monitor for the pt taking "poetin" drugs
monitor RBC's
major SE of hydroxyurea
myelosupression
which patients would the nurse suspect to be prescribed sevelamir?
renal pts
medication that binds to phosphate to balance phosphate and calcium levels
sevelamir
what is hydroxyuria used for?
sickle cell
what should the nurse monitor in the patient taking allopurinol
uric acid