BIO CHAP 5

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Inhibition of an enzyme is irreversible when

covalent bonds form between inhibitor and enzyme.

Most cellular work is accomplished by _____ energizing molecules by _____ them.

ATP ... phosphorylating

Which of the following is an accurate comparison of active transport and facilitated diffusion?

Active transport moves solutes against their concentration gradient; facilitated diffusion moves substances down their concentration gradient.

In plant cells, carbon dioxide and water are joined to form carbohydrates. Plant cells can also break down carbohydrates such as glucose, releasing carbon dioxide, water, and energy. No one has ever observed such reactions between water and carbon dioxide outside of living cells. What allows simple molecules to assemble into more complex molecules, and also disassemble, in cells but not in other, nonbiological environments?

Cells couple energy-releasing reactions to energy-requiring reactions.

Which of these statements describes what occurs in facilitated diffusion?

Facilitated diffusion of solutes occurs through protein pores in the membrane.

In a theoretical world where all things are possible, how could you increase the amount of energy that could be stored in a molecule of ATP?

Increase the negative charge of each phosphate group.

Which of these statements about enzyme inhibitors is true?

The action of competitive inhibitors may be reversible or irreversible.

The hydrolysis of DNA into nucleotides constitutes an exergonic reaction. Yet, DNA is quite stable. Why is this the case?

The activation energy required to initiate this reaction is seldom reached.

Which of the following is an example of the second law of thermodynamics?

The aerobic respiration of glucose generates heat.

According to the second law of thermodynamics, which of the following is true?

The ordering of one system depends on the disordering of another.

Lactase is essential for digesting lactose in milk. This enzyme is specific for this sugar. Why?

There is a precise compatibility between the active site and the lactose molecule.

When in solution, a molecule that moves slowly across an artificial membrane moves rapidly across a plasma membrane. This molecule rapidly enters the cell regardless of whether its concentration is higher inside or outside the cell. Using this information, which transport mechanism is most likely to be responsible for the movement of the molecule across a plasma membrane?

active transport

Cellular respiration is an example of __________.

an exergonic process

Cells store energy that they use for work in the _____.

arrangement of atoms within molecules

During enzymatic reactions, substrates are converted to products. A property of enzymes that facilitates this reaction is that they are catalysts and therefore _____.

change the rate of a reaction without being consumed by the reaction

Azidothymidine (AZT) is an antiretroviral drug used in the treatment of HIV. It shares a structural similarity to a nucleotide. What might be the mode of action for this drug?

competitive inhibition

A nursing infant is able to obtain disease-fighting antibodies, which are large protein molecules, from its mother's milk. These molecules probably enter the cells lining the baby's digestive tract via __________.

endocytosis

What condition might result from an excess of aquaporins?

fluid retention in pregnant women

In the process of osmosis, water displays a net movement from an area of __________ water concentration to an area of __________ water concentration.

higher ... lower

New drugs are being developed to lower levels of circulating cholesterol. A successful drug would be one that _____.

increases the rate of LDL receptor-mediated endocytosis

Light is _____ energy, which is converted into _____ energy by plants

kinetic ... chemical

The synthesis of an amino acid follows this pathway: precursor A > intermediate B > amino acid C. Each reaction is catalyzed by a different enzyme. This metabolic pathway is controlled by feedback inhibition with amino acid C inhibiting the conversion of precursor A to intermediate B. Amino acid C acts as a _____ of the first enzyme in the pathway.

noncompetitive inhibitor

Overall, membranes seem to have a great deal in common, but on closer inspection it is revealed that membranes of different cells have unique properties. What is the primary component of membranes that gives membranes cell-specific properties?

proteins

For an enzyme to catalyze a reaction there must be a specific fit between the __________ and the enzyme's __________.

substrate ... active site

The transport of molecules of a particular solute from inside an animal cell across the cell membrane to the extracellular fluid always requires energy when _____.

the concentration of the solute is lower inside the cell than outside it

Which of the following statements is true of an exergonic reaction, but NOT true of an endergonic reaction?

the potential energy of the products is less than the potential energy of the reactants

Aquaporins are proteins that facilitate the transport of __________ across the membrane.

water


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