Blood Bank Chap.2 HW

Which of the following components in the complement cascade mediates the lysis of the target cells? a. C1qrs b. C4a, C3a, and C5a c. C5 to C9 d. C3a and C3b

C5 to C9

Hemolysis was observed at room temperature when testing a patient's serum with reagent red cells used for screening. When this test was repeated using the patient's plasma, no hemolysis was observed. What was the most likely explanation for the different reactions? a. The plasma sample was collected incorrectly. b. The serum sample was contaminated. c. Complement activation was inhibited by calcium in the plasma sample. d. The serum sample was fresher.

Complement activation was inhibited by calcium in the plasma sample

What is the potential effect in a tube agglutination test if a red cell suspension with a concentration greater than 5% is used? a. False negatives b. False positives c. Hemolysis d. No effect

False negative

A technologist added 4 drops of a 5% red cell suspension instead of the required 1 drop to a hemagglutination test. What is the potential consequence to the test results? a. False-positive b. False-negative c. Hemolysis due to complement activation d. Test results are not affected

False-negative

What part of the immunoglobulin molecule distinguishes the isotype? a. Light chain b. Heavy chain c. Kappa chain d. Lambda chain

Heavy chain

Which immunoglobulin class is impacted by the zeta potential in a hemagglutination test? a. IgM b. IgG c. IgA d. IgE

IgG

Which of the following requires adjustment in order to enhance the reaction of an antibody in vitro? a. Temperature above 37 C b. Speed of the centrifuge above the calibrated settings c. Increase the concentration of red cells in the test system d. Increase the incubation time in the incubator

Increase the incubation time in the incubator

What biological molecules are considered the most immunogenic? a. Carbohydrates b. Lipids c. Proteins d. Enzymes

Proteins

Extravascular destruction of blood cells occurs in the: a. blood vessels. b. lymph nodes. c. spleen. d. thymus.

spleen

After adding antigen and antibody to a test tube, one large agglutinate was observed. How should this reaction be graded? a. 2+ b. 3+ c. 4+ d. 0

4+