Brucellosis

Symptoms appear ____ days after exposure

5-60 days

Vaccine is very effective at preventing _____ which prevents further transmission

abortions

New animals should be

isolated and tested

Animal brucellosis diagnostic tests

- rapid slide agglutination test - Rose Bengal Plate test - Indirect-ELISA - complement fixation test

Human brucellosis serological tests

- standard agglutination test - Coombs test - Indirect fluorescence antibody test - ELISA

Overall mortality in acute or chronic cases of brucellosis is very low - ___%

2-5%

Scientific name

Brucella abortus, Brucella melitensis, Brucella canis, Brucella ovis, Brucella neotomae, Brucella microti

Strain of Brucella that typically affects humans is ________ but B. suis, B. abortus, and B. canis all have zoonotic ability

Brucella melitensis

Seen with severe cases

CNS and lining of heart affected

Eradication program in the U.S.

Cooperative State Federal Brucellosis Eradication Program

Licensed vaccine used in nonpregnant female cattle 4-12 months of age

RB51

Brucella is usually spread through contact with infected

birthing tissues and fluids

Brucellosis is a bacterial disease caused by various Brucella species, which mainly infect

cattle, swine, goats, sheep, and dogs

Species involved

cattle, swine, goats, sheep, dogs, deer, elk, humans

Disease is transmitted from animals to humans by

consuming unpasteurized milk and dairy, consuming undercooked meat, or skin penetration

Brucellosis is considered one of the most serious disease of livestock due to

damage done by the infection

Major damage

decreased milk production, weight loss, loss of young, infertility, and lameness

Arrange ______ for exposed and potentially infected animals

diagnostic workups, necropsies, or both

Common flu-like symptoms seen

fever, sweats, headaches, back pain, physical weakness

_____- like symptoms

flu-like symptoms

Humans generally acquire the disease through direct contact with

infected animals, eating or drinking contaminated animal products, or inhaling airborne agents

bacteria can be found in

milk, blood, urine, semen

Aborted cattle fetuses show

necrosis of cotyledons

most common complication/morbidity

osteoarticular involvment

Antemortem skin lesions are

papulonodular and maculopapular eruptions with erythema nodosum-like lesions

PCR is very reliable at determining Brucella in ______ but it's expensive so less common

peripheral blood and tissues

Apparent lowering of fertility with

poor conception rates, retained afterbirths with resulting uterine infections, and (occasionally) enlarged, arthritic joints

Management

proper sanitation, PPE, and herd management

Brucellosis also known as

remitting fever, undulant fever, Mediterranean fever, Maltese fever, Gibraltar fever, Crimean fever, goat fever, Bang disease

It can affect many different organs including

repro system, liver, heart, CNS

Detection of Brucella species by culture can sometimes be unsuccessful so ______ is preferred

serological testing

Serious disease due to rapidity of ______ and it being ______

spread, zoonotic

The primary human serological test used in lab settings is the

standard agglutination test

True or False: recommended to not use a singular antibiotic to treat but instead a combo or staggering

true

Geographic location

worldwide but mostly eradicated in U.S.