Ch 50 Antineoplastic and Targeted Therapies

28. A client is receiving cisplatin. Based on the nurse's understanding that this drug can be nephrotoxic, the nurse anticipates that the primary health care provider will prescribe which of the following?

aminofostone

A nurse is caring for a client being treated with antineoplastic drugs. The client is at risk for thrombocytopenia due to bone marrow suppression. The nurse would assess the client for which of the following?

bloody urine

When assessing the client for leukopenia, the nurse

monitros the client for fever, sore throat, and chills

Which intervention woul dbe most helpful for a client with stomatitis

proved frequent mout care with normal saline

Which is most common symptom of extravasion

swelling around injection

A client is receiving an alkylating agent. Which of the following would be used? Select all that apply.

B) Chlorambucil (Leukeran) D) Cyclophosphamide (Cytoxan) E) Ifosfamide (Ifex)

Which of the following are examples of immediate adverse reactions to an antineoplastic drug that the nurse should discuss with the client prior to drug administration? Select all that apply.

B) Extravasion C) Naseau

A group of nursing students are reviewing antineoplastic drugs. The students demonstrate understanding of the information when they identify which of the following as cell cycle specific? Select all that apply.

B) Plant alkaloids C) Antimetabolites

Which of the following alkylating agents can cross the blood-brain barrier? Select all that apply.

C) Carmustine (BiCNU) D) Streptozocin (Zanosar)

Cancerous cell grow when

G0 phase of the cell cycles is skipped

Which phase in cell cycle splits into two daughter cells

M

The nurse is providing care to a client with anorexia due to antineoplastic therapy. The nurse identifies a nursing diagnosis of Imbalanced Nutrition: Less Than Body Requirements. Which of the following would be least appropriate for the nurse to include in the client's plan of care?

Offering fatty foods to stimulate the taste buds

After teaching a group of nursing students about the cell cycle and how it relates to antineoplastic drugs, the instructor determines that the teaching was successful when the students identify which phase of the cell cycle as being affected by antimetabolites?

S phase

Which advers to antineoplastic drugs is most likely to affect the clients body image

alopecia

Which drug listed is most likely to cause N/V

cisplatin

A client has been diagnosed with cancer. The physician prescribes antineoplastic drug therapy to the client. Which of the following would the nurse include in the discussion about the prescribed therapy?

delays sprad of cancer to other sites

Which finding woul dbe most indicative to the nurse that the client has thrombocytopenia

easy bruising

A client visits the health care facility for information on cancer. The client asks the nurse if regular consumption of green tea can cause harm. Which of the following should the nurse inform the client as possible effects of green tea?

insomnia

A client is to start chemotherapy. The client is worried about going bald in the course of the treatment. How can the nurse assist the client in being comfortable with her body image?

suggest use of wig or cap

24. A nurse is caring for a client who is at risk for erythema during antineoplastic drug therapy. The nurse identifies a nursing diagnosis of Impaired Tissue Integrity. Which of the following would be appropriate to suggest?

wear loose protective clothing

10. Which of the following cytoprotective agents can be given along with antineoplastic drugs to help prevent or lessen certain adverse effects? Select all that apply.

A) Allopurinol (Zyloprim) B) Amifostine (Ethyol) C) Leucovorin (Wellcovorin) D) Mesna (Mesnex) E) Dexrazoxane (Zinecard)

A nurse should understand that which of the following adverse effects of antineoplastic drugs are related to the death of rapidly growing cells? Select all that apply.

A) Alopecia B) Leukopenia C) Stomatitis E) Thrombocytopenia

A nurse notifies the primary health care provider because assessment reveals signs of thrombocytopenia, including which of the following? Select all that apply.

A) Bleeding gums B) Petechiae C) Tarry stools D) Hematuria E) Coffee-ground emesis

The primary health care provider prescribes an antineoplastic antibiotic. The nurse identifies which of the following as a possibility? Select all that apply.

A) Bleomycin (Blenoxane) C) Dactinomycin (Cosmegen) D) Daunorubicin (DaunoXome)

14. After administering an antineoplastic drug, the nurse bases the ongoing assessment on which of the following factors? Select all that apply.

A) Client's general condition B) Client's individual response to the drug C) Adverse reactions that may occur D) Guidelines established by the oncology physician or clinic E) Results of periodic laboratory tests and radiographic scans

A nurse is discussing the possible adverse reactions that may occur with antineoplastic therapy. Which of the following would the nurse discuss as examples of long-term adverse reactions? Select all that apply

A) Fertility problems E) Cardiotoxicity

15. If the nurse has to clean up a spill of antineoplastic drug, which of the following personal protective equipment should be worn? Select all that apply.

A) Gloves B) Safety goggles C) Gown E) NIOSH-approved respirator

A nurse is caring for a client who is prescribed Velban, a vinca alkaloid. The client asks the nurse about how the drug acts. Which of the following would the nurse integrate into the response?

A) Interference with amino acid production in the S phase

2. A nurse is preparing to administer an antineoplastic drug that is classified as an antimetabolite. Which of the following might the nurse be preparing to give? Select all that apply.

A) Mercaptopurine (Purinethol) B) Capecitabine (Xeloda) C) Fluorouracil (Adrucil)

A nurse should monitor a client closely for signs of worsening atrial fibrillation when which of the following antineoplastic drugs are used concomitantly with digoxin (Lanoxin)? Select all that apply.

A) Mercaptopurine (Purinethol) D) Doxorubicin (Doxil) E) Irinotecan (Camptosar)

18. A client is receiving doxorubicin. The nurse suspects that extravasation has occurred based on assessment of which of the following? Select all that apply.

A) Swelling C) Lack of blood return E) Redness

The nurse suspects that a client is developing leukopenia and notifies the primary health care provider based on assessment of which of the following? Select all that apply.

A) Temperature of 100.4°F or higher B) Cough C) Sore throat D) Frequent urination E) White blood cell count of less than 2500/mm3

1. After teaching a group of nursing students about antineoplastic drugs, the instructor determines that the teaching was successful when the students identify which of the following as being classified as a plant alkaloid? Select all that apply.

A) Vincristine (Oncovin) C) Paclitaxel (Taxol) D) Etoposide (Toposar) E) Irinotecan (Camptosar)

A nurse should monitor a client closely for increased seizure activity when which of the following antineoplastic drugs are used concomitantly with phenytoin (Dilantin)? Select all that apply.

B) Busulfan (Busulfex) C) Thiotepa (Thioplex) E) Irinotecan (Camptosar)

A client has been prescribed melphalan for the treatment of an ovarian tumor. The client wants to know how the drug acts. Which of the following would the nurse integrate into the response?

B) Change to a more alkaline cell environment

Which of the following should be included in the nurse's preadministration assessment before administering the first dose of an antineoplastic drug? Select all that apply

B) Weight D) Blood pressure E) Temperature

A nurse is caring for a client undergoing treatment with plant alkaloids for cancer. The client is also receiving warfarin for a history of atrial fibrillation. The nurse would monitor the client for which of the following as a possible interaction?

increased risk for prolonged bleeding

A client has been receiving treatment with antineoplastic drugs that depress the bone marrow. Which preadministration assessment would be most important for the nurse to complete with respect to this effect?

obtain CBC