Chapter 10: validity & reliability

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extraneous factors must be?

controlled or quantified

reliability

consistency of a specific measurement

how to measure quantitative data

instrumented devices, clinician measurement, clinician observation, pt self-report

the next 10 definitions are threats to

internal validity

multiple treatment interference

testing multiple variables might interfere with others Ex: so many tests on pt they tire & skew results

Intra-rating

testing of same person with same tester on a different day (tester doesn't change)

how to ensure objective results?

the design of an experiment to test the hypothesis must be unbiased

the less generalizable the study results are to the general population

the harder it is for external validity

blinding is pertinent to?

the internal validity of a study

Blinding is important to

the internal validity of the study

fidelity of intervention is an example of

the reliability of the independent variable (in an intervention study)

internal validity refers to?

the validity of a study's experimental design

Testing

"practice" or "learning" effect Ex: child given test multiple times & learns items

Intertester reliability (interrater reliability)

-ability of different testers to produce consistent repeated measures of a test

Accuracy

-closeness of measured value to true value of what is being assessed (Precision is dividing up a number again & again)

Intraclass correlation coefficients (ICCs)

-estimates reliability for measure of continuous data -scale of 0-1

construct validity

-how well a specific measure or scale captures a defined entity -stems form psychology, but may be used in health science

Concurrent Validity

-how well one measure correlates with an existing gold standard -important to be established for new measures aiming to assess the same properties as an existing test

when is validity discussed in an experiment?

-in relation to the structure of the overall design -the measurements preformed -the intervention assessed

Discriminative validity

-indicative of a given measure's lack of correlation or divergence from existing measures that it should not be related to Ex: specificity & sensitivity testing

instrument accuracy

-instruments must be valid & reliable -multiple people collecting data affects results (Interrater reliability) -sloppy data-gathering accefts results (intrarater reliability)

how to tightly control a study

-subject selection -administration of interventions -control of confounding factors

Consent validity

-the amount that a particular measure represents all facets of the construct it is supposed to measure -more scientifically rigorous than face validity Ex: items add up to one particular construct like an intelligence or concussion test

artificial nature of experimental condition

-the more artificial the environment, the less generalizable

Bias

-threat to internal validity -may be inherent to subjects or experimenters

Face validity

-whether a specific measure actually assesses what it's designed to measure -issue in developing "functional tests" for pts in rehab

measurement data is classified into 3 types

1. Categorical -you can or cannot (9 or 1) 2. Ordinal- measures how well it was done 3. Continuous -standardized measure

what are the two pain threats of internal validity?

1. Threats of the participants 2. threats of the measurement

4 threats to external validity

1. effects of pretesting 2. subject & Tx interaction 3. artificial nature of experiment 4. multiple Tx ingerference

we must measure fidelity to confirm?

1. interventionists adhere to intervention 2. key ingredients making intervention unique 3. differentiation of this intervention from another intervention

how to optimize external validity (limit desired generalization)

1. larger population 2. other outcomes (dependent variables) 3. other conditions (independent variables) 4. other setting

3 types of blinding

1. subjects 2. members of experimental team 3. clinicians treating pts

4 types of error

1. unreliable & invalid 2. unreliable & valid 3. reliable & invalid 4. reliable & valid

internal validity should be thought of as along a continuum rather than

a dichotomous property

Categorical or Nominal data involves?

a finite number of classification for observation -numeric value assigned to each category -order of numbers assigned to each category is inconsequential

"Intra-tester reliability" (intra-rater reliability, test-retest reliability)

ability of same tester to produce consistent, repeated measures of a test

face validity is determined subjectively

and often by expert opinion

Pearson's r

assesses association between two continuous measures across a sample of subjects -indicates that scores on the two measures are highly correlated -does NOT assess systematic error, or show the scores of 2 measures are systematically diverging from each other

Selection

biases resulting from pre-existing differences between history & selection Ex: males taking tampon surveys

Ordinal data uses?

categories -order of numeric classification is of consequence Ex: Likert scales, in which a numeric value is assigned to each possible response (face pain scale)

Selection Bias

characteristics that subjects have before they enroll in a study (age, injury, illness) that influences the results

Delimitations

decisions that investigators make to improve the internal validity of their studies

error variance

difference between true score & observed score

mortality

differential attrition from groups

controlling confounding factors does what to internal validity?

enhances it

bias can be avoided by?

ensuring subjects in different group shave similar characteristics by random assignment or matching procedure

sources of error include?

error or biological variability by the subject, or error by the tester or instrumentation used to take the measure

Agreement

estimates consistency or reproducibility of categorical data

History

events concurrent with independent variable effecting the dependent Ex: unknown variable is exposed & researcher is aware

confounding variables

extraneous factors that may result in false relationships

statistical regression

extreme scores tend to regress to the mean over time Ex: evaluating mean of the 3pt scorer to the game today

subject & treatment interaction

group selection biases -> will it generalize other groups Ex: being too selective with pts, must be a smoker, obese, with arthritis...

Precision of measurement

how confident one is in the reproducibility of a measure -takes into account ICC & standard deviation

when is the study's validity questioned?

if other factors are influencing the dependent variable

placebo effect

improvement due to expectation

Hawthorne effect

improvement due to observation... changing something because you know people are watching

Continuous Data

measured on a scale that can continuously be broken down into smaller & smaller increments

convergent validity

measures whether a given measure is highly correlated with other measures of the same construct Ex: balance measures strength & other things

maturation

processes occurring within subjects as a result of time instead of the independent variable

Inter-rating

rating between two people or having two different people run the test

threats associated with measurement

regression, instrumentation, testing effect

External Validity

relates to the degree to which the results of a study are generalizable to the real world

what are 2 measure of key components of validity

reliability & agreement

Intrarater & interrater agreement are defined the same as?

reliability measure

kappa statistic

reports the estimation of agreement ranging from 0-1 indicating perfect agreement

validity is an inherent principle in?

research design

Halo effect

researcher has expectations about performance of the subject

threats associated with participants

selection, maturation, attrition, history

Precision is reported as?

standard error of measurement (SEM) in the unit of measure

Ecological validity

translating treatments from controlled lab studies to typical clinical practice

Effects of pretesting

treatment may have it's own effect if preceded by a pretest (making treatment generalizable only under those conditions) Ex: calling attention to problem like posture, they may try to correct it

total variance is due to

true variance & error variance

what is the key quantitative inquiry?

unbiased & objective measurement of the dependent variables

true variance

variability between subjects

double-blinded

when both researchers and participants are blinded

when does Pearson's r approach 1?

when one measure increases in value and the second measure increases incrementally

when is the ICC lower?

when systematic error is present

when is a study valid?

when the independent variable proves to have a definite effect on the dependent

Internal Validity

where the independent variable is responsible for observed effects on the dependent variable


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