Chapter 14
A young man asks the nurse about the goal of the cancer therapy his mother is reveiving. What is the nurse's best response?
"The goal is to limit the cancer cells so the immune system can respond without causing too much toxicity to your mother"
Hormones and Hormone modulators
-Abiraterone -Anastrazole -Bicalutamide -Degarelix -Enzalutamide -Estramustine -Exemestane -Flutamide -Fulvestrant -Goserelin -Histrelin -Letrozole -Leuprolide -Megestrol -Mitotane -Nilutamide -Tamoxifen * -Toremifene -Triptorelin Pamoate
Cancer Cell-Specific Agents
-Afatinib -Axitinib -Bortezomib -Bosutinib -Cabozantinib -Ceretinib -Crizotinib -Dabrafenib -Erlotinib -Everolimus -Ibrutinib -Idelalisib -Imatinib * -Lapatinib -Nilotinib -Palbociclib -Pazopanib -Ponatinib -Regorafenib -Ruxolitinib -Sorafenib -Sunitinib -Temsirolimus -Vemurafenib -Ziv-aflibercept
Antineoplastic Adjunctive Therapy
-Allopurinol -Amifostine -Dexarazoxane -Leucovorin -Levoleucovorin -Mesna -Rasburicase
Alkylating Agents
-Altremtamine -Bendamustine -Busulfan -Carboplatin -Carmustine -Chlorambucil * -Cisplatin -Cyclophosphamide -Decarbazine -Ifosfamide -Lomustine -Mechlorethamine -Melphalan -Oxaliplatin -Procarbazine -Streptozocin -Temozolomide
Miscellaneous Antineoplastics
-Arsenic Trioxide -Asparaginase (Erwinia chrysanthemi) -Azacitidine -Belinostat -Bexarotene -Decitabine -Hydroxyurea -Irinotecan -Nelarabine -Omacetaxine -Pegaspargase -Profimer -Romidepsin -Sipuleucel -Talc powder -Topotecan -Tretinoin -Vismodegib -Vorinostat
Antineoplastic Antibiotics
-Bleomycin -Dactinomycin -Daunorubicin -Doxorubicin * -Epirubicin -Idarubicin -Mitomycin -Mitoxantrone -Valrubicin
Mitotic Inhibitors
-Cabazitaxel -Docetaxel -Eribulin -Etoposide -Ixabepilone -Paclitaxel -Teniposide -Vinblastine -Vincristine * -Vinorelbine
Antimetabolites
-Capecitabine -Cladribine -Clofarabine -Cytarabine -Floxuridine -Fludarabine -Fluorouracil -Gemcitabine -Mercaptopurine -Methotrexate * -Pemetrexed -Penostatin -Pralatrexate -Thioguanine
A client is experiencing intense nausea while being treated with chemotherapeutics. What actions should the nurse perform?
-Ensure that the client has had a dietician consult -Administer antiemetics as prescribed -Provide the client with small, frequent meals
The nurse is conducting a class for oncologic nurses. What characteristics of chemotherapy for older adults should the nurse identify?
-Older adults may be more susceptible to the central nervous system (CNS) and GI effects of these drugs -Older clients are at risk for dehydration and diminished nutritional status -Older adults are already somewhat immunosuppressed, so further suppression is a concern
A client with breast cancer will have radiation therapy and then begin chemotherapy. Drug therapy will consist of a combination of doxorubicin, cyclophosphamide, and paclitaxel. What should the nurse include in the client's teaching plan concerning the drug therapy?
-Take special care when shaving or when brushing her teeth (Cuts = bleeding) -Avoid large crowds and public places whenever possible (immunocompromised)
Chlorambucil has been ordered for a client with Hodgkin's disease. The nurse should assess what domains when monitoring for adverse effects?
-Tremors -Muscle twitching -Confusion
A nurse is preparing an antineoplastic agent for a school-aged client who has leukemia. What action related to the administration of this drug should the nurse perform first?
Check laboratory studies to determine most recent measures of bone marrow function.
A 39-year-old client has begun taking tamoxifen to reduce the risk of contralateral breast cancer. The client is now reporting hot flashes and dysmenorrhea. What is the nurse's best action?
Inform the client that these are likely adverse effects of drug therapy
The client has just been started on an alkylating agent to treat testicular cancer. What assessment finding would suggest that the client is experiencing a common adverse effect of this medication?
The client's most recent laboratory results indicate pancytopenia (all cell low/deficient)
A client with Hodgkin's disease has been prescribed vincristine. What nursing consideration should the nurse prioritize when administering this drug?
The nurse should avoid any skin, eye, or mucous membrane contact with the drug.
A female client has been prescribed methotrexate for meningeal leukemia. What health education should the nurse prioritze?
Use reliable forms of barrier contraception (no oral contraception)
